What they do:
AI drug discovery platform for neurotherapeutics
Quick facts:
HQ: San Francisco, CA, United States
Funding:
$2.16M · Options · Feb 2026
Y Combinator Winter 2025 Startups
This list has 166 startups and was last updated on Oct 15, 2026. 68 of them are hiring right now. Biggest hubs: San Francisco (103), New York (19), and London (6). Largest teams: Spott, AfterQuery, and Mundo AI. Latest round: Exin Therapeutics raised $2.16M (Feb 10, 2026).
166 startupsPage 1 of 5
Spott
Hiring
What they do:
AI-native ATS/CRM for recruiting firms
Quick facts:
HQ: Leuven, Belgium
AfterQuery
Hiring
What they do:
Applied research lab curating data solutions for foundation model…
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The data layer for perceptual intelligence
Quick facts:
Harper
Hiring
What they do:
AI-native commercial insurance brokerage
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The Javascript framework for building AI agents, from the Gatsby devs
Quick facts:
HQ: San Francisco, CA, United States
HUD
Hiring
What they do:
Platform and marketplace for RL environments and AI data
Quick facts:
HQ: San Francisco, CA, United States
Forge Automation
Hiring
What they do:
Software Enabled CNC Parts Supplier
Quick facts:
Contrario
Hiring
What they do:
AI hiring platform powered by expert recruiters
Quick facts:
HQ: San Francisco, CA, United States
Mercura
Hiring
What they do:
AI Quote and Order Automation for Distributors & Manufacturers
Quick facts:
HQ: Germany
Cifrato
Hiring
What they do:
AI Accountant for Accounting Firms
Quick facts:
Weave
Hiring
What they do:
AI to understand and then route engineering work
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Agents for Accelerated Clinical Trial Design
Quick facts:
HQ: Boston, MA, United States
What they do:
Query mission-critical video
Quick facts:
Toothy AI
Hiring
What they do:
AI for insurance verification & billing at dental clinics
Quick facts:
HQ: San Francisco, CA, United States
SalesPatriot
Hiring
What they do:
Supply chain superintelligence for distribution and procurement
Quick facts:
HQ: San Francisco, CA, United States
Calltree
Hiring
What they do:
Enterprise-grade AI support reps for call centers
Quick facts:
HQ: San Francisco, CA, United States
Leaping AI
Hiring
What they do:
AI voice and texting agents
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Foundational model of human societies for consequential decisions
Quick facts:
HQ: London, United Kingdom
AthenaHQ
Hiring
What they do:
Be the Answer in AI Search - AI SEO across SEO, GEO & AEO
Quick facts:
HQ: San Francisco, CA, United States
Fuse AI
Hiring
What they do:
Agentic Sales Platform
Quick facts:
HQ: San Francisco, CA, United States
Reditus Space
Hiring
What they do:
Reusable Satellites
Quick facts:
HQ: Atlanta, GA, United States
Closure
Hiring
What they do:
We help law enforcement solve crime
Quick facts:
HQ: New York, NY, United States
YouShift
Hiring
What they do:
The OS for hospital workforce management
Quick facts:
HQ: New York, NY, United States
HealthKey
Hiring
What they do:
AI-powered Patient Identification for Clinical Trials
Quick facts:
HQ: Austin, TX, United States
Orbital Operations
Hiring
What they do:
High Thrust Space Vehicles for Satellite Defense
Quick facts:
HQ: Los Angeles, CA, United States
Proception Inc
Hiring
What they do:
Making humanoids dexterous enough to thread a needle
Quick facts:
HQ: San Francisco, CA, United States
SAMMY Labs
Hiring
What they do:
Computational Law
Quick facts:
HQ: London, United Kingdom
Bild AI
Hiring
What they do:
AI estimating & detailing for Division 8 doors, frames & hardware
Quick facts:
HQ: San Francisco, CA, United States
Splash Inc.
Hiring
What they do:
Autonomous patrol-boats for National Security
Quick facts:
HQ: Los Angeles, CA, United States
Ergo
Hiring
What they do:
Ergo is the context layer that helps revenue teams close more deals.
Quick facts:
HQ: San Francisco, CA, United States
Scout
Hiring
What they do:
AI-powered student information system for K-12 schools
Quick facts:
HQ: New York, NY, United States
What they do:
Discovering new pesticides with AI
Quick facts:
HQ: San Francisco, CA, United States
Nitrode
Hiring
What they do:
Frontier AI research to advance game development
Quick facts:
HQ: San Francisco, CA, United States
Optifye.ai
Hiring
What they do:
AI performance monitoring for factory workers
Quick facts:
Woz
Hiring
What they do:
Claude Code plugin that reduces token consumption and cost by 50%
Quick facts:
HQ: San Francisco, CA, United States
Questions and answers
How many startups are on this list?
There are 166 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
68 of them are hiring right now, including Spott, AfterQuery, and Harper.
Which of them have the largest teams?
By team size: Spott (50 employees), AfterQuery (30 employees), and Mundo AI (30 employees).
Which of them raised money recently?
Latest rounds: Exin Therapeutics — $2.16M Options (Feb 2026).
Where are they based?
The biggest hubs are San Francisco (103), New York (19), and London (6).