Craftwork
Hiring
What they do:
Digital-native home painting franchise
Quick facts:
HQ: Charlotte, NC, United States
Top Startups in North Carolina
This list has 48 startups and was last updated on Oct 15, 2026. 5 of them are hiring right now. Biggest hubs: Durham (13), Charlotte (12), and Raleigh (10). Largest teams: Craftwork, Lucid Bots, and Finmark. Latest round: NN raised $53.1M (Oct 14, 2026).
48 startupsPage 1 of 2
What they do:
We build robots for dull, dirty, and dangerous jobs.
Quick facts:
HQ: Charlotte, NC, United States
Data Driven Bioscience
Hiring
What they do:
Cancer Diagnosis 10X faster, 10X cheaper
Quick facts:
HQ: Durham, NC, United States
BotBuilt
Hiring
What they do:
We use robots to build houses.
Quick facts:
HQ: Southern Pines, NC, United States
What they do:
7 Cups is an emotional support service that matches up people that…
Quick facts:
HQ: Charlotte, NC, United States
What they do:
Next-gen airline OS
Quick facts:
HQ: Raleigh, NC, United States
What they do:
Fully autonomous defense solutions for the global edge.
Quick facts:
HQ: Raleigh, NC, United States
Lumius
Hiring
What they do:
Fast, smart, accessible 3D ultrasound that anyone can use
Quick facts:
HQ: Durham, NC, United States
What they do:
Recover from any outage in 10 minutes or less.
Quick facts:
HQ: Durham, NC, United States
Synapse Semiconductor
Hiring
What they do:
New semiconductors that merge compute and vision
Quick facts:
HQ: Durham, NC, United States
What they do:
Farm Genetics Made Easy - Using DNA and Software
Quick facts:
HQ: Asheville, NC, United States
What they do:
Helping Plastic Surgeons Rebuild Fat
Quick facts:
HQ: Durham, NC, United States
Quick facts:
HQ: Charlotte, NC, United States
Funding:
$53.1M · Equity · Oct 2026
Quick facts:
HQ: Raleigh, NC, United States
Funding:
$36M · Equity · Oct 2026
Quick facts:
HQ: Morrisville, NC, United States
Incorporated: 2022
Funding:
$30M · Equity + debt · Mar 2026
Quick facts:
HQ: Durham, NC, United States
Funding:
$26M · Equity · Mar 2026
Quick facts:
HQ: Mars Hill, NC, United States
Funding:
$25M · Equity · Mar 2026
Quick facts:
HQ: Raleigh, NC, United States
Incorporated: 2022
Funding:
$17.2M · Equity · Apr 2026
Quick facts:
HQ: Morrisville, NC, United States
Funding:
$10.8M · Equity · Jan 2026
Quick facts:
HQ: Durham, NC, United States
Incorporated: 2021
Funding:
$10M · Equity · Apr 2026
Quick facts:
HQ: Morrisville, NC, United States
Incorporated: 2022
Funding:
$8.46M · SAFE · Oct 2026
Quick facts:
HQ: Davidson, NC, United States
Funding:
$8.4M · Equity · Mar 2026
Quick facts:
HQ: Morrisville, NC, United States
Incorporated: 2026
Funding:
$7.85M · Debt · Feb 2026
Quick facts:
HQ: Charlotte, NC, United States
Incorporated: 2022
Funding:
$7.47M · Equity · Oct 2026
Quick facts:
HQ: Charlotte, NC, United States
Incorporated: 2025
Funding:
$6M · Apr 2026
Quick facts:
HQ: Fleetwood, NC, United States
Incorporated: 2021
Funding:
$5.7M · Equity · Jan 2026
Quick facts:
HQ: Pittsboro, NC, United States
Funding:
$5.46M · Equity · Feb 2026
Quick facts:
HQ: Durham, NC, United States
Incorporated: 2021
Funding:
$5.41M · Equity · Feb 2026
Quick facts:
HQ: Holly Springs, NC, United States
Incorporated: 2025
Funding:
$5M · Equity · Jan 2026
Quick facts:
HQ: Forest City, NC, United States
Funding:
$5M · Debt · May 2026
Quick facts:
HQ: Raleigh, NC, United States
Incorporated: 2022
Funding:
$4.72M · Equity · Feb 2026
Quick facts:
HQ: Durham, NC, United States
Funding:
$3.65M · Equity · Mar 2026
Quick facts:
HQ: Raleigh, NC, United States
Incorporated: 2025
Funding:
$3.31M · SAFE · Jan 2026
Quick facts:
HQ: Durham, NC, United States
Funding:
$3.02M · Equity · Jun 2026
Quick facts:
HQ: Charlotte, NC, United States
Incorporated: 2021
Funding:
$2.94M · Equity · Apr 2026
Quick facts:
HQ: Charlotte, NC, United States
Incorporated: 2025
Funding:
$2.62M · Equity · Mar 2026
Questions and answers
How many startups are on this list?
There are 48 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
5 of them are hiring right now, including Craftwork, Data Driven Bioscience, and BotBuilt.
Which of them have the largest teams?
By team size: Craftwork (50 employees), Lucid Bots (26 employees), and Finmark (14 employees).
Which of them raised money recently?
Latest rounds: NN — $53.1M Equity (Oct 2026), Optain Health — $7.47M Equity (Oct 2026), and Archaius — $8.46M SAFE (Oct 2026).
Where are they based?
The biggest hubs are Durham (13), Charlotte (12), and Raleigh (10).