
What they do:
digital mortgage closing
Quick facts:
HQ: Portland, OR, United States
This list has 33 startups and was last updated on Oct 15, 2026. Biggest hubs: Portland (15), Remote (4), and Bend (4). Largest teams: Snapdocs, CareRev, and gaiia. Latest round: Spiritus raised $66.1K (Oct 13, 2026).

What they do:
digital mortgage closing
Quick facts:
HQ: Portland, OR, United States

What they do:
all-in-one operating system (OS) for telcos
Quick facts:
HQ: Remote, OR, United States

What they do:
API-first banking for ambitious technology companies.
Quick facts:
HQ: Bend, OR, United States

What they do:
Make all team work visible — people and AI agents
Quick facts:
HQ: Remote, OR, United States

What they do:
We recycle plastic using engineered enzymes
Quick facts:
HQ: Portland, OR, United States

What they do:
Human whole body end-of-life preservation for later revival.
Quick facts:
HQ: Portland, OR, United States

What they do:
Utilizing monogenic disorders to inform and solve highly complex…
Quick facts:
HQ: Portland, OR, United States

What they do:
Replacing organ transplant with an infusion
Quick facts:
HQ: Bend, OR, United States

What they do:
Smart electric & water meters as a service
Quick facts:
HQ: Remote, OR, United States

What they do:
Skyscrape makes temperature-responsive insulation
Quick facts:
HQ: Portland, OR, United States

What they do:
Collaborative workspace for internal tools and agents
Quick facts:
HQ: Eugene, OR, United States
Quick facts:
HQ: Beaverton, OR, United States
Funding:
$47.8M · Equity · Jun 2026
Quick facts:
HQ: Portland, OR, United States
Funding:
$8.25M · Equity · Jun 2026
Quick facts:
HQ: Beaverton, OR, United States
Funding:
$7.5M · Equity · Mar 2026
Quick facts:
HQ: Portland, OR, United States
Funding:
$7M · Equity · Jun 2026
Quick facts:
HQ: Corvallis, OR, United States
Funding:
$4.94M · Equity · Apr 2026
Quick facts:
HQ: Corvallis, OR, United States
Funding:
$4.7M · Equity · Jan 2026
Quick facts:
HQ: Beaverton, OR, United States
Funding:
$3.3M · Equity · Jan 2026
Quick facts:
HQ: Beaverton, OR, United States
Funding:
$3.2M · SAFE · Apr 2026
Quick facts:
HQ: Bend, OR, United States
Funding:
$1.77M · Options · Jan 2026
Quick facts:
HQ: Bend, OR, United States
Funding:
$1.5M · Equity · Mar 2026
Quick facts:
HQ: Milwaukie, OR, United States
Funding:
$66.1K · Equity · Oct 2026

What they do:
Seamlessly connecting healthcare facilities and professionals through…
Quick facts:
HQ: Remote, OR, United States

What they do:
Direct real estate investing marketplace
Quick facts:
HQ: Portland, OR, United States

What they do:
Automating all IT operations
Quick facts:
HQ: Portland, OR, United States

What they do:
Modern healthcare for kids. Pediatric Primary, Urgent & Remote Care.
Quick facts:
HQ: Portland, OR, United States

What they do:
Get Food From Farmers, Delivered.
Quick facts:
HQ: Portland, OR, United States

What they do:
Data Quality & Playback Platform
Quick facts:
HQ: Portland, OR, United States

What they do:
Accelerating machine learning through software
Quick facts:
HQ: Portland, OR, United States

What they do:
We filter distracting emails away from your inbox.
Quick facts:
HQ: Portland, OR, United States
What they do:
Writewith is a collaborative writing web app, enabling you to easily flow through the steps of writing, editing, and publishing a document with a group. A…
Quick facts:
HQ: Corvallis, OR, United States

What they do:
Open source build tool for monorepos and large codebases
Quick facts:
HQ: Portland, OR, United States

What they do:
The AI accountability agent for startup founders
Quick facts:
HQ: Lake Oswego, OR, United States
There are 33 startups on this list, last updated on Oct 15, 2026.
None of them shows open roles right now.
By team size: Snapdocs (285 employees), CareRev (275 employees), and gaiia (100 employees).
Latest rounds: Spiritus — $66.1K Equity (Oct 2026), Forest City Trading Group — $8.25M Equity (Jun 2026), and Ceek Women's Health — $7M Equity (Jun 2026).
The biggest hubs are Portland (15), Remote (4), and Bend (4).