What they do:
OpenClaw for manufacturers
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HQ: San Francisco, CA, United States
Top B2B Startups
This list has 3,431 startups and was last updated on Oct 15, 2026. 897 of them are hiring right now. Biggest hubs: San Francisco (1,811), New York (387), and London (120). Largest teams: Deel, 99minutos, and GrubMarket. Latest round: Onebrief raised $151M (Oct 14, 2026).
3,431 startupsPage 64 of 96
What they do:
Defining the frontier of multiplayer AI.
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HQ: San Francisco, CA, United States
What they do:
Market for future inference capacity
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HQ: San Francisco, CA, United States
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AI-powered freight brokerage. Quote, book, and track loads in seconds.
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HQ: San Francisco, CA, United States
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CrowdStrike for AI Agents
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HQ: San Francisco, CA, United States
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Quant Neolab building self-improving agents from quant data
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HQ: San Francisco, CA, United States
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AI-native freight brokerage
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HQ: San Francisco, CA, United States
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AI Operating System for Wholesale Distribution
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HQ: San Francisco, CA, United States
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Databricks for Enterprise Codebases
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HQ: San Francisco, CA, United States
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Legora for AEC (Architecture, Engineering, & Construction) firms
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HQ: San Francisco, CA, United States
What they do:
The world's frontier hacker of AI agents.
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HQ: San Francisco, CA, United States
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AI-Native Insurance for Frontier Tech
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HQ: San Francisco, CA, United States
What they do:
Predict how market participants behave
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HQ: San Francisco, CA, United States
What they do:
Expert computer-use data for frontier AI labs
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What they do:
We find where AI agents fail, then train better models to run them.
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HQ: San Francisco, CA, United States
What they do:
The AI-native radiology practice
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HQ: San Francisco, CA, United States
What they do:
The Bloomberg of Loans
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HQ: San Francisco, CA, United States
What they do:
Hotels that run themselves
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HQ: San Francisco, CA, United States
What they do:
The AI Operating System for Auto Shops.
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HQ: San Francisco, CA, United States
What they do:
Training company-specific models that approve AI actions.
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HQ: San Francisco, CA, United States
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AI Brokers for Industrial Trade
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HQ: San Francisco, CA, United States
What they do:
Helping startups win gov contracts
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HQ: San Francisco, CA, United States
What they do:
Multiplayer workspace for agents and humans
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HQ: San Francisco, CA, United States
What they do:
Distributed, hardware-agnostic AI inference
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HQ: San Francisco, CA, United States
What they do:
Self-optimizing inference cloud for faster, cheaper AI
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HQ: San Francisco, CA, United States
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The frontier data platform for aligned health and biological AI
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HQ: London, United Kingdom
What they do:
AI tools for the chips your AI runs on
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HQ: San Francisco, CA, United States
What they do:
Next-generation agent operating system
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HQ: San Francisco, CA, United States
What they do:
The biggest crowdsourced benchmark for Computer-Use
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HQ: San Francisco, CA, United States
What they do:
AI that works for in-house legal teams
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HQ: San Francisco, CA, United States
What they do:
Open source AI gateway that turns your traffic into better models
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HQ: San Francisco, CA, United States
What they do:
Test agents in realistic worlds built from production usage
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HQ: San Francisco, CA, United States
What they do:
On-device AI that knows your entire life and does your work overnight.
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HQ: San Francisco, CA, United States
What they do:
AI users that test your app on every device and browser
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HQ: San Francisco, CA, United States
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A factory for small and specialized video reasoning models
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What they do:
World's Earliest Test for Alzheimer's Biomarkers
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HQ: San Francisco, CA, United States