What they do:
High-precision, closed-loop neuromodulation devices
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HQ: Boston, MA, United States
Top Medical Devices Startups
This list has 74 startups and was last updated on Oct 15, 2026. 11 of them are hiring right now. Biggest hubs: San Francisco (25), Houston (6), and New York (5). Largest teams: PNOĒ, BBy, and Morphle Labs. Latest round: VenoStent raised $10M (May 1, 2026).
74 startupsPage 2 of 3
What they do:
Platform injectable gel based therapeutic for osteoarthritis
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HQ: Galway, Ireland
What they do:
Helping Plastic Surgeons Rebuild Fat
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HQ: Durham, NC, United States
What they do:
Semi-Autonomous Diagnostics for Emergent Care
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HQ: FL, United States
What they do:
Natural hydrogel to keep internal organs scar-free after surgery
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HQ: Houston, TX, United States
What they do:
Catheter-based solution to treat chronic heart failure.
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HQ: Houston, TX, United States
What they do:
Helping physicians select the right therapy for breast cancer patients
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HQ: Austin, TX, United States
What they do:
HelpWear is striving to better at-home healthcare by developing affordable and accessible products for patients all around the world. HelpWear is currently…
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What they do:
Neurostimulation implant to restore hearing & speech understanding
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HQ: San Francisco, CA, United States
What they do:
Reinventing respiration monitoring
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HQ: Los Angeles, CA, United States
What they do:
CRM Co-Pilot for Medtech Sales
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HQ: San Francisco, CA, United States
What they do:
Higher resolution MRI with faster scan times.
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HQ: New York, NY, United States
What they do:
Redefining the Standard of Care for Iron Deficiency Anemia
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HQ: San Francisco, CA, United States
What they do:
Next-Generation Surgical Navigation and Robotics
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HQ: Boston, MA, United States
YC S19Early stage
Spire Health
Acquired
What they do:
Remote patient monitoring for lung disease patients.
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HQ: San Francisco, CA, United States
Atomic Alchemy
Acquired
What they do:
We produce cancer-curing materials used in nuclear medicine.
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HQ: Idaho Falls, ID, United States
Mable
Acquired
What they do:
First personalized migraine clinic using genetics and telehealth.
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HQ: London, United Kingdom
Shift Labs
Acquired
What they do:
Makers of simple, affordable medical devices. Our award-winning…
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HQ: Seattle, WA, United States
Sepsis Scout
Acquired
What they do:
Wearables and AI to predict and prevent sepsis outside the hospital
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HQ: San Francisco, CA, United States
UroDev Medical
Acquired
What they do:
Devices to improve the quality of life for people with Spinal Cord…
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HQ: San Clemente, CA, United States
Voyage Biomedical
Acquired
What they do:
Using cooling to end brain damage during stroke.
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HQ: San Francisco, CA, United States
Nexa Labs
Acquired
What they do:
Implantable microchips and AI for cattle monitoring
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HQ: San Francisco, CA, United States
MedXT
Acquired
What they do:
Radiology in the cloud. X-rays, CAT scans, MRI's, and…
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HQ: San Francisco, CA, United States
Luminist Labs
Acquired
What they do:
Diagnostic platform for early detection of liver disease
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HQ: New York, NY, United States
Allotrope Medical
Acquired
What they do:
Advancing surgical precision through safe electrical stimulation.
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HQ: Houston, TX, United States
Voodoo Manufacturing
Shut down
What they do:
AWS for manufacturing.
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HQ: New York, NY, United States
Medinas Health
Shut down
What they do:
Medinas helps hospitals manage their inventory and buy and sell their…
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HQ: San Francisco, CA, United States
Klarismo
Shut down
What they do:
Klarismo turns your body into an interactive experience. We built a…
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HQ: San Francisco, CA, United States
Clip Health
Shut down
What they do:
Testing & treatment at home, in minutes, for chronic & acute disease
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HQ: San Francisco, CA, United States
Standard Cyborg
Shut down
What they do:
Buid, test and deploy perception applications
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HQ: San Francisco, CA, United States
InnoVein
Shut down
What they do:
We cure intractable leg wounds with a replacement valve for veins.
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HQ: San Francisco, CA, United States
Penta Medical
Shut down
What they do:
Smart hardware for injury recovery.
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AudioFocus
Shut down
What they do:
Hearing aids that work in noisy places, like restaurants, using ML.
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HQ: San Francisco, CA, United States
Quadrant Eye
Shut down
What they do:
Breaking new ground in online eyecare.
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HQ: San Francisco, CA, United States
V-Flow Medical
Shut down
What they do:
Transforming the lives of millions of women suffering from chronic…
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HQ: San Clemente, CA, United States
Zeit Medical
Shut down
What they do:
Immediate stroke detection at home
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HQ: San Francisco, CA, United States