What they do:
Robots that learn on the job
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HQ: San Francisco, CA, United States
Top AI & Data Startups in the United States
This list has 2,134 startups and was last updated on Oct 15, 2026. 661 of them are hiring right now. Biggest hubs: San Francisco (1,471), New York (339), and Los Angeles (51). Largest teams: Cruise, Relativity Space, and Fivetran. Latest round: Safi Analytics raised $22.4M (Oct 14, 2026).
2,134 startupsPage 43 of 60
What they do:
AI agents for compliance at institutional trading firms
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HQ: San Francisco, CA, United States
What they do:
Multiplayer workspace for agents and humans
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HQ: San Francisco, CA, United States
What they do:
Distributed, hardware-agnostic AI inference
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HQ: San Francisco, CA, United States
What they do:
Self-optimizing inference cloud for faster, cheaper AI
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HQ: San Francisco, CA, United States
What they do:
Foundational infrastructure for Physical AI
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HQ: San Francisco, CA, United States
What they do:
Autonomous rovers to make the ‘Google Maps’ of underground utilities
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HQ: San Francisco, CA, United States
What they do:
Duolingo for learning anything
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HQ: San Francisco, CA, United States
What they do:
Automatic Diagnosis & Fix for Industrial Automation Cells
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HQ: San Francisco, CA, United States
What they do:
AI tools for the chips your AI runs on
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HQ: San Francisco, CA, United States
What they do:
Next-generation agent operating system
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HQ: San Francisco, CA, United States
What they do:
The biggest crowdsourced benchmark for Computer-Use
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HQ: San Francisco, CA, United States
What they do:
Open source AI gateway that turns your traffic into better models
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HQ: San Francisco, CA, United States
What they do:
Test agents in realistic worlds built from production usage
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HQ: San Francisco, CA, United States
What they do:
On-device AI that knows your entire life and does your work overnight.
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HQ: San Francisco, CA, United States
What they do:
AI users that test your app on every device and browser
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HQ: San Francisco, CA, United States
What they do:
World's Earliest Test for Alzheimer's Biomarkers
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HQ: San Francisco, CA, United States
What they do:
Lakehouse-as-a-Service (LaaS)
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HQ: San Francisco, CA, United States
What they do:
Agents running industrial enterprises from back office to shop floor
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HQ: San Francisco, CA, United States
What they do:
AI for the industries that power America.
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HQ: San Francisco, CA, United States
What they do:
Intelligent Cloud for AI workloads
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HQ: San Francisco, CA, United States
What they do:
Give AI agents the right context at the right moment
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HQ: San Francisco, CA, United States
What they do:
Automate on-call at agent-scale.
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HQ: San Francisco, CA, United States
What they do:
Building in-house, frontier AI labs for companies
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HQ: San Francisco, CA, United States
What they do:
The AI desktop.
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HQ: San Francisco, CA, United States
What they do:
Fast inference for voice
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HQ: San Francisco, CA, United States
What they do:
The AI coding agent for C and C++
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HQ: San Francisco, CA, United States
What they do:
The infrastructure to run coding agents for your team
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HQ: San Francisco, CA, United States
What they do:
A consumer brain-computer interface you can map to anything.
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HQ: San Francisco, CA, United States
What they do:
AI agents that run law firm operations.
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HQ: San Francisco, CA, United States
What they do:
The people data company for the agent era
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HQ: San Francisco, CA, United States
What they do:
API simulators for testing and training agents locally
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HQ: San Francisco, CA, United States
What they do:
A foundation model for engineering physics
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HQ: San Francisco, CA, United States
What they do:
Turn any website into an MCP for your agents, in minutes
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HQ: San Francisco, CA, United States
What they do:
AI Claims Investigator for Insurance
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HQ: New York, NY, United States
What they do:
Reconero helps police officers automate their workflows with AI
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HQ: San Francisco, CA, United States