DoorDash
HiringPublic
What they do:
Restaurant delivery.
Quick facts:
HQ: San Francisco, CA, United States
Top Deep Tech Startups in the United States
This list has 1,386 startups and was last updated on Oct 15, 2026. 306 of them are hiring right now. Biggest hubs: San Francisco (704), New York (137), and Los Angeles (79). Largest teams: DoorDash, EquipmentShare, and GrubMarket. Latest round: Onebrief raised $151M (Oct 14, 2026).
1,386 startupsPage 1 of 39
EquipmentShare
HiringPublic
What they do:
Cloud solutions for the construction industry.
Quick facts:
HQ: Columbia, MO, United States
What they do:
AI-powered technology enabler and digital transformer of American…
Quick facts:
HQ: San Francisco, CA, United States
Instacart
HiringPublic
What they do:
Marketplace for grocery delivery and pickup
Quick facts:
HQ: San Francisco, CA, United States
Flexport
Hiring
What they do:
Platform for global logistics.
Quick facts:
HQ: San Francisco, CA, United States
Flock Safety
Hiring
What they do:
The first public safety operating system that eliminates crime.
Quick facts:
HQ: Atlanta, GA, United States
Ginkgo Bioworks
HiringPublic
What they do:
Our mission is to make biology easier to engineer.
Quick facts:
HQ: Boston, MA, United States
Odeko
Hiring
What they do:
Our operations software makes it easier to run--and grow--your cafe
Quick facts:
HQ: New York, NY, United States
Presto
Public
What they do:
Digital meets physical for big chain restaurants
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Tech-powered women's wellness.
Quick facts:
HQ: San Francisco, CA, United States
Momentus
Public
What they do:
The space infrastructure services company
Quick facts:
HQ: San Francisco, CA, United States
Rigetti Computing
Public
What they do:
Quantum coherent supercomputing.
Quick facts:
HQ: San Francisco, CA, United States
Oklo
Public
What they do:
Emission free, always on power from advanced fission power plants.
Quick facts:
HQ: San Francisco, CA, United States
ShipBob
Hiring
What they do:
Providing Amazon level logistics to e-commerce businesses.
Quick facts:
HQ: Chicago, IL, United States
Pardes Biosciences
Public
What they do:
We break viruses
Quick facts:
HQ: San Francisco, CA, United States
Relativity Space
Hiring
What they do:
Building humanity’s multiplanetary future.
Quick facts:
HQ: Los Angeles, CA, United States
Nabis
Hiring
What they do:
Nabis is the largest licensed cannabis wholesale platform.
Quick facts:
HQ: New York, NY, United States
What they do:
The management platform for the short term rental industry.
Quick facts:
HQ: New York, NY, United States
Tractian
Hiring
What they do:
Physical AI for asset-heavy industries
Quick facts:
HQ: Atlanta, GA, United States
Astranis
Hiring
What they do:
Advanced satellites for high orbits.
Quick facts:
HQ: San Francisco, CA, United States
Tovala
Hiring
What they do:
A smart-oven-paired subscription meal service.
Quick facts:
HQ: Chicago, IL, United States
Stoke Space
Hiring
What they do:
Seamless mobility to, through, and from space. It starts with 100%…
Quick facts:
HQ: Seattle, WA, United States
Embark Trucks
Public
What they do:
Self-driving semi trucks.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
We make robots for biologists.
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HQ: New York, NY, United States
What they do:
digital mortgage closing
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HQ: Portland, OR, United States
What they do:
Onebrief makes military headquarters run seamlessly
Quick facts:
HQ: Honolulu, HI, United States
Funding:
$151M · Equity · Oct 2026
May Mobility
Hiring
What they do:
Transforming cities and rural areas through AV transit and technology
Quick facts:
HQ: Ann Arbor, MI, United States
What they do:
The everything app for LATAM
Quick facts:
HQ: Los Angeles, CA, United States
Gecko Robotics
Hiring
What they do:
AI + Robotics for the Built World
Quick facts:
HQ: Pittsburgh, PA, United States
What they do:
Economically and environmentally sustainable supersonic travel
Quick facts:
HQ: Denver, CO, United States
Handle
Hiring
What they do:
Simplifying Payments and Compliance for Construction Suppliers
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Inspection software for renewable energy & sustainable infrastructure
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Decarbonizing the chemicals industry.
Quick facts:
HQ: Houston, TX, United States
Vetcove
Hiring
What they do:
Powering the animal health supply chain.
Quick facts:
HQ: Miami, FL, United States
What they do:
Robotic Process Automation and Document Processing Platform
Quick facts:
HQ: Austin, TX, United States
Remi
Hiring
What they do:
Simplifying roofing for homeowners, roofers and enterprises.
Quick facts:
HQ: Lehi, UT, United States
Questions and answers
How many startups are on this list?
There are 1,386 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
306 of them are hiring right now, including DoorDash, EquipmentShare, and Instacart.
Which of them have the largest teams?
By team size: DoorDash (8,600 employees), EquipmentShare (5,400 employees), and GrubMarket (4,548 employees).
Which of them raised money recently?
Latest rounds: Onebrief — $151M Equity (Oct 2026), Circularity Fuels — $8.79M Equity (Oct 2026), and NN — $53.1M Equity (Oct 2026).
Where are they based?
The biggest hubs are San Francisco (704), New York (137), and Los Angeles (79).