Rootly
Hiring
What they do:
AI-native on-call and incident response carefully crafted to help…
Quick facts:
HQ: San Francisco, CA, United States
Top AI Infrastructure Startups in California
This list has 52 startups and was last updated on Oct 15, 2026. 13 of them are hiring right now. Largest teams: Rootly, Domu Technology Inc., and Middleware. Latest round: Thunder GPU raised $15.7M (Jun 16, 2026).
52 startupsPage 1 of 2
Domu Technology Inc.
Hiring
What they do:
AI Agents for collections
Quick facts:
HQ: San Francisco, CA, United States
Middleware
Hiring
What they do:
AI-based full stack observability platform
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HQ: San Francisco, CA, United States
What they do:
Open-source, serverless vectordb for production-scale generative AI
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HQ: San Francisco, CA, United States
Respan
Hiring
What they do:
Self-driving observability, evals, and gateway for AI agents
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HQ: San Francisco, CA, United States
LiteLLM
Hiring
What they do:
Call every LLM API like it's OpenAI [100+ LLMs]
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HQ: San Francisco, CA, United States
What they do:
Frontier coding data for training and evaluating LLMs
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HQ: San Francisco, CA, United States
What they do:
The fastest way to ship airtight AI
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HQ: San Francisco, CA, United States
Wordware
Hiring
What they do:
AI agents you can rely on
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HQ: San Francisco, CA, United States
Zensors
Hiring
What they do:
AI to understand and automates the physical world
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HQ: San Francisco, CA, United States
Besimple AI
Hiring
What they do:
Voice data for AI
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HQ: San Francisco, CA, United States
Abundant
Hiring
What they do:
Agent simulation and RL for researchers
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HQ: San Francisco, CA, United States
Luminal
Hiring
What they do:
Making AI run fast on any hardware.
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HQ: San Francisco, CA, United States
What they do:
Inference for real-time voice and chat
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HQ: San Francisco, CA, United States
Orca Aerospace
Hiring
What they do:
AI spacecraft operators that lives onboard the vehicle
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HQ: San Francisco, CA, United States
What they do:
AI engineer that debugs and fixes production incidents in realtime
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HQ: San Francisco, CA, United States
Covera
Hiring
What they do:
AI-native OS for insurance brokers
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HQ: San Francisco, CA, United States
What they do:
No-Code LLM Application / Workflow Builder
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HQ: San Francisco, CA, United States
Adaptional
Hiring
What they do:
AI-powered insurance claims review
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HQ: San Francisco, CA, United States
YC S25Early stage
What they do:
Grok bot for GTM & Revenue teams
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HQ: San Francisco, CA, United States
What they do:
Infuse knowledge into language models with just 10 samples
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HQ: San Francisco, CA, United States
What they do:
AI back office for food product quality teams
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HQ: Los Angeles, CA, United States
What they do:
Foundation Model for Chemical Manufacturing
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HQ: San Francisco, CA, United States
What they do:
Automating home care agency operations with AI
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HQ: San Francisco, CA, United States
What they do:
The COLD Task Framework
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HQ: San Francisco, CA, United States
What they do:
Open-source frontier models for knowledge work
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HQ: San Francisco, CA, United States
What they do:
Specialized AI for Critical Industries
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HQ: San Francisco, CA, United States
What they do:
Model Agnostic AI coworker in Slack
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HQ: San Francisco, CA, United States
What they do:
An AI-operated logistics company.
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HQ: San Francisco, CA, United States
What they do:
Continuous optimization for AI agents
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HQ: San Francisco, CA, United States
What they do:
Deploy Machine Learning Models with One Command
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HQ: San Francisco, CA, United States
What they do:
Observability and evaluation platform for LLM apps.
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HQ: San Francisco, CA, United States
What they do:
Effortless AI automation for business operations
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HQ: San Francisco, CA, United States
What they do:
AI Agents for Platform Engineering
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HQ: San Francisco, CA, United States
What they do:
AI SRE agent that triages, coordinates, and fixes production incidents
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HQ: San Francisco, CA, United States
What they do:
AI Cost Management: Track and attribute AI spend across every provider
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HQ: San Francisco, CA, United States
Questions and answers
How many startups are on this list?
There are 52 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
13 of them are hiring right now, including Rootly, Domu Technology Inc., and Middleware.
Which of them have the largest teams?
By team size: Rootly (75 employees), Domu Technology Inc. (50 employees), and Middleware (40 employees).
Which of them raised money recently?
Latest rounds: Thunder GPU — $15.7M Equity (Jun 2026).