99minutos
Hiring
What they do:
The fastest shipping for online shopping
Quick facts:
HQ: Mexico City, Mexico
Top B2B Software Startups in Mexico
This list has 35 startups and was last updated on Oct 15, 2026. 5 of them are hiring right now. Biggest hubs: Mexico City (23), Monterrey (9), and Guadalajara (2). Largest teams: 99minutos, Kapital Bank, and SkydropX.
35 startups
What they do:
Empowering businesses to grow.
Quick facts:
HQ: Mexico City, Mexico
What they do:
Logistic Management System for E-commerce & Retail in Mexico.
Quick facts:
What they do:
Learning Hub for companies in Latam
Quick facts:
HQ: Mexico City, Mexico
What they do:
One-stop-shop for restaurants to operate and grow their business.
Quick facts:
What they do:
Lattice for Latam with personalized learning and development
Quick facts:
Runa
Hiring
What they do:
Automating payroll for Latin America.
Quick facts:
HQ: Mexico City, Mexico
What they do:
We help Accountants automate work and serve their customers online
Quick facts:
What they do:
The one-stop-shop for auto-parts in Mexico.
Quick facts:
HQ: Mexico City, Mexico
What they do:
Tax Automation Infrastructure
Quick facts:
HQ: Mexico City, Mexico
What they do:
Livement makes selling tickets for events easy and safe for organizers
Quick facts:
HQ: Guadalajara, Mexico
What they do:
The operating system for restaurants in LatAm.
Quick facts:
What they do:
Turbotax for México and LATAM
Quick facts:
What they do:
Retaining employees in LatAm via education
Quick facts:
Shuttle Central
Hiring
What they do:
Helping travel companies to sell transportation online
Quick facts:
HQ: Cancún, Mexico
PoloTab
Hiring
What they do:
Restaurant software that actually works
Quick facts:
HQ: Mexico City, Mexico
What they do:
The Work Number for LatAm
Quick facts:
HQ: Mexico City, Mexico
What they do:
Salary on-demand platform for Latin America
Quick facts:
What they do:
AI-native direct booking infrastructure for global hospitality
Quick facts:
HQ: Mexico City, Mexico
What they do:
Voice AI Agents for Debt Collection
Quick facts:
HQ: Mexico City, Mexico
Helios
Hiring
What they do:
Create your AI workforce
Quick facts:
HQ: Mexico City, Mexico
What they do:
Workflows to empower employees to spend while finance stay in control
Quick facts:
HQ: Mexico City, Mexico
What they do:
Realtime Data Connectors
Quick facts:
HQ: Mexico City, Mexico
What they do:
AI agents that recover lost revenue through real conversations.
Quick facts:
HQ: Mexico City, Mexico
R2
Acquired
What they do:
Embedded lending infrastructure
Quick facts:
HQ: Mexico City, Mexico
Plerk
Acquired
What they do:
Acquired by Minu.mx - Fintech solutions for employees, starting with…
Quick facts:
HQ: Guadalajara, Mexico
delt.ai
Acquired
What they do:
Digital banking for businesses in Latam.
Quick facts:
HQ: Mexico City, Mexico
Hilos
Acquired
What they do:
Close and activate your customers on WhatsApp
Quick facts:
HQ: Mexico City, Mexico
boitas.com
Shut down
What they do:
Largest B2B eCommerce platform for SMBs in Latin America.
Quick facts:
Alana
Shut down
What they do:
Staff management software for retail, manufacturing and hospitality
Quick facts:
HQ: Mexico City, Mexico
Alima
Shut down
What they do:
Fresh procurement made easy
Quick facts:
HQ: Mexico City, Mexico
Levo
Shut down
What they do:
Treasury management platform for SMBs to optimize idle cash in Latam
Quick facts:
HQ: Mexico City, Mexico
Valari
Shut down
What they do:
Embedded finance platform for LatAm.
Quick facts:
HQ: Mexico City, Mexico
Mipos.dev
Shut down
What they do:
Api that let you connect all the restaurant tech services in Latam
Quick facts:
HQ: Mexico City, Mexico
YC S19Early stage
MarcoPolo
Shut down
What they do:
Alibaba for Latin America
Quick facts:
HQ: Mexico City, Mexico
YC W21Early stage
Questions and answers
How many startups are on this list?
There are 35 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
5 of them are hiring right now, including 99minutos, Runa, and Shuttle Central.
Which of them have the largest teams?
By team size: 99minutos (5,000 employees), Kapital Bank (3,600 employees), and SkydropX (320 employees).
Where are they based?
The biggest hubs are Mexico City (23), Monterrey (9), and Guadalajara (2).