Ginkgo Bioworks
HiringPublic
What they do:
Our mission is to make biology easier to engineer.
Quick facts:
HQ: Boston, MA, United States
Top B2B Software Startups in Massachusetts
This list has 99 startups and was last updated on Oct 15, 2026. 6 of them are hiring right now. Biggest hubs: Boston (65), Cambridge (13), and Burlington (3). Largest teams: Ginkgo Bioworks, TetraScience, and Cloudant. Latest round: Arkea Bio raised $15M (Oct 9, 2026).
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What they do:
The only R&D data cloud for life sciences
Quick facts:
HQ: Boston, MA, United States
Kodex
Hiring
What they do:
Easiest way for companies to process data requests from governments
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HQ: Boston, MA, United States
Alpha Vantage
Hiring
What they do:
Developer-friendly and enterprise-grade APIs for financial market…
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HQ: Boston, MA, United States
What they do:
The AI Support Agent for Ecommerce
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HQ: Boston, MA, United States
Vector
Hiring
What they do:
Advertising for the new internet
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HQ: Boston, MA, United States
What they do:
Event marketing CRM
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HQ: Boston, MA, United States
What they do:
Data integration & insights for state and local governments
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HQ: Boston, MA, United States
What they do:
Agents for Accelerated Clinical Trial Design
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HQ: Boston, MA, United States
What they do:
Non-profit building open-source voting machines for US elections.
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HQ: Boston, MA, United States
Upsolve
Hiring
What they do:
Helping low-income Americans overcome debt and rebuild credit at…
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HQ: Boston, MA, United States
What they do:
Enterprise-Grade OpenTelemetry
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HQ: Boston, MA, United States
Maven Bio
Hiring
What they do:
Live intelligence for biopharma teams.
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HQ: Boston, MA, United States
What they do:
Population health analytics powered by wastewater.
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HQ: Boston, MA, United States
What they do:
Ravn is building a heads-up display for soldiers.
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HQ: Boston, MA, United States
What they do:
Accelerate verifiable computing
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HQ: Boston, MA, United States
What they do:
Create custom NLP models
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HQ: Boston, MA, United States
What they do:
Plaid for Commercial Real Estate
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HQ: Boston, MA, United States
What they do:
Simulate your customers with AI agents
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HQ: Boston, MA, United States
What they do:
An open-source operating system for reliable long-running agents
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HQ: Boston, MA, United States
What they do:
Robots for the inspection and maintenance of data centers
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HQ: Boston, MA, United States
What they do:
The AI-Native Consumer + Plaintiff Law Firm
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HQ: Boston, MA, United States
What they do:
The IDE for Tokenmaxxers
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HQ: Boston, MA, United States
What they do:
Open source alternative to Semrush and Ahrefs
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HQ: Boston, MA, United States
What they do:
Infrastructure Cartography
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HQ: Boston, MA, United States
Quick facts:
HQ: Cambridge, MA, United States
Incorporated: 2023
Funding:
$189M · Equity · May 2026
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2022
Funding:
$187M · Equity · May 2026
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2023
Funding:
$123M · Equity · Mar 2026
Quick facts:
HQ: Boston, MA, United States
Funding:
$103M · Equity · Apr 2026
Quick facts:
HQ: Brookline, MA, United States
Funding:
$101M · Equity · Jan 2026
Quick facts:
HQ: Boston, MA, United States
Funding:
$46.7M · Equity · May 2026
Quick facts:
HQ: Charlestown, MA, United States
Incorporated: 2021
Funding:
$43.7M · Equity · Jan 2026
Quick facts:
HQ: Burlington, MA, United States
Funding:
$35.5M · Equity · Jun 2026
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2021
Funding:
$29.7M · Equity · Jun 2026
Quick facts:
HQ: Billerica, MA, United States
Funding:
$21.6M · Equity + debt · Apr 2026
Quick facts:
HQ: Burlington, MA, United States
Incorporated: 2024
Funding:
$20M · Equity · Feb 2026
Questions and answers
How many startups are on this list?
There are 99 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
6 of them are hiring right now, including Ginkgo Bioworks, Kodex, and Alpha Vantage.
Which of them have the largest teams?
By team size: Ginkgo Bioworks (641 employees), TetraScience (100 employees), and Cloudant (51 employees).
Which of them raised money recently?
Latest rounds: Arkea Bio — $15M Equity (Oct 2026), Flexxbotics — $1.8M Equity (Oct 2026), and Cambridge Heavy Industries — $7.16M Equity (Oct 2026).
Where are they based?
The biggest hubs are Boston (65), Cambridge (13), and Burlington (3).