Resquared
Hiring
What they do:
Marketing automation platform for selling to local businesses.
Quick facts:
HQ: Philadelphia, PA, United States
Top B2B Software Startups in Philadelphia
This list has 11 startups and was last updated on Oct 15, 2026. 3 of them are hiring right now. Largest teams: Resquared, Nextmv, and FIRST. Latest round: Beneration raised $3.32M (Apr 6, 2026).
11 startups
FIRST
Hiring
What they do:
The best way for any business to offer delivery.
Quick facts:
HQ: Philadelphia, PA, United States
Orchid
Hiring
What they do:
AI-powered EHR for independent mental health professionals
Quick facts:
HQ: Philadelphia, PA, United States
What they do:
The SAFE for commercial contracts
Quick facts:
HQ: Philadelphia, PA, United States
What they do:
Converting biology into digital molecular maps
Quick facts:
HQ: Philadelphia, PA, United States
Quick facts:
HQ: Philadelphia, PA, United States
Funding:
$197M · Equity · Jan 2026
Quick facts:
HQ: Philadelphia, PA, United States
Incorporated: 2023
Funding:
$8.67M · Equity · Jan 2026
Quick facts:
HQ: Philadelphia, PA, United States
Funding:
$3.32M · Equity + debt · Apr 2026
Nextmv
Acquired
What they do:
A DecisionOps platform that accelerates optimization AI teams
Quick facts:
HQ: Philadelphia, PA, United States
Chatter
Acquired
What they do:
Dead simple LLM testing and iteration
Quick facts:
HQ: Philadelphia, PA, United States
Buzzle
Shut down
What they do:
Automatic voice-of-customer trends & metrics from sales conversations.
Quick facts:
HQ: Philadelphia, PA, United States
Questions and answers
How many startups are on this list?
There are 11 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
3 of them are hiring right now, including Resquared, FIRST, and Orchid.
Which of them have the largest teams?
By team size: Resquared (40 employees), Nextmv (22 employees), and FIRST (12 employees).
Which of them raised money recently?
Latest rounds: Beneration — $3.32M Equity + debt (Apr 2026), True Talent Advisory — $197M Equity (Jan 2026), and True Talent Advisory Management — $8.67M Equity (Jan 2026).