What they do:
MedCrypt gives medical device vendors cybersecurity features in a few…
Quick facts:
HQ: San Diego, CA, United States
Top B2B Software Startups in San Diego
This list has 12 startups and was last updated on Oct 15, 2026. Largest teams: MedCrypt, Rethoric, and Intersect Labs. Latest round: Smart Home Protection raised $2.66M (Oct 14, 2026).
12 startups
What they do:
LinkedIn content consultancy and scheduling platform for busy founders
Quick facts:
HQ: San Diego, CA, United States
What they do:
Faster processors for solving NP-complete problems
Quick facts:
HQ: San Diego, CA, United States
Quick facts:
HQ: San Diego, CA, United States
Funding:
$592M · Equity · May 2026
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HQ: San Diego, CA, United States
Funding:
$130M · Equity · Feb 2026
Quick facts:
HQ: San Diego, CA, United States
Funding:
$56M · Equity · Jan 2026
Quick facts:
HQ: San Diego, CA, United States
Incorporated: 2022
Funding:
$35M · Equity · Mar 2026
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HQ: San Diego, CA, United States
Funding:
$6.8M · Equity · May 2026
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HQ: San Diego, CA, United States
Funding:
$4.45M · Debt · Jan 2026
Quick facts:
HQ: San Diego, CA, United States
Funding:
$2.66M · Equity · Oct 2026
Quick facts:
HQ: San Diego, CA, United States
Incorporated: 2022
Funding:
$278K · Equity · Oct 2026
Intersect Labs
Acquired
What they do:
Collaborative data noteboook for business teams
Quick facts:
HQ: San Diego, CA, United States
Questions and answers
How many startups are on this list?
There are 12 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
None of them shows open roles right now.
Which of them have the largest teams?
By team size: MedCrypt (16 employees), Rethoric (4 employees), and Intersect Labs (4 employees).
Which of them raised money recently?
Latest rounds: Smart Home Protection — $2.66M Equity (Oct 2026), M&R Technology — $278K Equity (Oct 2026), and Ferret Systems — $6.8M Equity (May 2026).