What they do:
AI native financial institution
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HQ: San Francisco, CA, United States
Y Combinator Spring 2025 Startups
This list has 144 startups and was last updated on Oct 15, 2026. 60 of them are hiring right now. Biggest hubs: San Francisco (84), New York (20), and London (13). Largest teams: throxy, Auctor, and Synthio Labs. Latest round: Sygaldry Technologies raised $139M (Apr 14, 2026).
144 startupsPage 3 of 4
What they do:
AI-powered robotics for scientific lab automation.
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HQ: San Francisco, CA, United States
What they do:
Encrypted AI with verifiable privacy
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HQ: San Francisco, CA, United States
What they do:
Turn scattered data into one platform for decision-making
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HQ: San Francisco, CA, United States
What they do:
Realtime Sales Copilot
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What they do:
chrt is a logistics platform for time-critical shipping
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HQ: Los Angeles, CA, United States
What they do:
AI agents for risk-bearing healthcare organizations
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HQ: San Francisco, CA, United States
What they do:
The authentication framework for TypeScript
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HQ: San Francisco, CA, United States
What they do:
Product Native Models
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HQ: San Francisco, CA, United States
What they do:
Streamlining Data Capture to Report Creation for Heavy Industries
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HQ: San Francisco, CA, United States
What they do:
AI financial auditors
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What they do:
Real-world company data for frontier AI
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HQ: San Francisco, CA, United States
What they do:
Gigascale Nanomanufacturing
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HQ: San Francisco, CA, United States
What they do:
AI Native Commercial Insurance Broker
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HQ: Philadelphia, PA, United States
What they do:
Custom models trained on your data
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HQ: San Francisco, CA, United States
What they do:
Creator marketing that scales like paid ads
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HQ: San Francisco, CA, United States
What they do:
AI tutor for each student.
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HQ: San Francisco, CA, United States
What they do:
We automate your entire product development lifecycle.
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HQ: San Francisco, CA, United States
What they do:
Open-source frontier models for knowledge work
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HQ: San Francisco, CA, United States
What they do:
AI-native financial institution for global businesses + agents.
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HQ: New York, NY, United States
What they do:
Understand your users beyond the numbers
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HQ: San Francisco, CA, United States
What they do:
Open-source semi-humanoid dev kit → home data → autonomy → 20h/wk
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HQ: Los Angeles, CA, United States
What they do:
A personal EA in your iMessage
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HQ: San Francisco, CA, United States
What they do:
Specialized AI for Critical Industries
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HQ: San Francisco, CA, United States
What they do:
Automatically write and update internal docs with every code commit.
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HQ: San Francisco, CA, United States
What they do:
Play the latest games in your browser with no downloads
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HQ: Los Angeles, CA, United States
What they do:
Self-Driving CI: fast AI-native GitHub Actions runners
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HQ: San Francisco, CA, United States
What they do:
AI Agents to win denied health insurance claims.
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HQ: San Francisco, CA, United States
What they do:
Environments for Long Horizon Work
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HQ: San Francisco, CA, United States
What they do:
AI generated podcasts
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HQ: London, United Kingdom
What they do:
RWE Generation in minutes
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HQ: San Francisco, CA, United States
What they do:
Simulation Engine for Benchmarking AI Products
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HQ: San Francisco, CA, United States
What they do:
Let your agent build dashboards and reporting.
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HQ: San Francisco, CA, United States
What they do:
The data gateway for agents.
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HQ: San Francisco, CA, United States
What they do:
Build governed AI agents on your own data, without code
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HQ: Switzerland
What they do:
AI agents that help you understand your customers' needs
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HQ: San Francisco, CA, United States