What they do:
Cursor for Email
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HQ: San Francisco, CA, United States
Y Combinator Summer 2025 Startups
This list has 166 startups and was last updated on Oct 15, 2026. 67 of them are hiring right now. Biggest hubs: San Francisco (113), New York (26), and London (3). Largest teams: Nox Metals, Flai, and GETASAP.
166 startupsPage 4 of 5
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Building medical school for AI Agents
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HQ: San Francisco, CA, United States
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Context-aware orchestration between humans and AI.
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HQ: London, United Kingdom
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AI content manager that grows your company's online presence
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HQ: San Francisco, CA, United States
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AI infrastructure for biosecurity
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HQ: New York, NY, United States
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AI for the physical world
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HQ: San Francisco, CA, United States
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The AI notepad that knows and works for you
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HQ: Seoul, South Korea
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AI Agents for E-commerce Customer Support
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HQ: Amsterdam, Netherlands
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Truckload Planning at Machine Precision
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HQ: San Francisco, CA, United States
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We audit medical claims for self-insured employers and health plans.
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HQ: New York, NY, United States
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AI-native real estate services firm
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HQ: Los Angeles, CA, United States
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AI-native software for managing rail and bulk operations.
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HQ: Olathe, KS, United States
What they do:
The makers of Klex Bots, your own team of digital coworkers.
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What they do:
Production infrastructure on autopilot
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HQ: San Francisco, CA, United States
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Digital transformation for real economy businesses
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HQ: San Francisco, CA, United States
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We provide hedge funds with information they can trade on
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HQ: San Francisco, CA, United States
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AI Shopping Agent for Your Ecommerce Store
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HQ: New York, NY, United States
What they do:
A better GItHub
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HQ: New York, NY, United States
What they do:
Sandboxes for AI agents
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HQ: San Francisco, CA, United States
What they do:
Independent AI evaluations lab
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HQ: New York, NY, United States
What they do:
Visibility and Controls for Browser Agents
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HQ: San Francisco, CA, United States
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The AI workspace for software implementations
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HQ: San Francisco, CA, United States
What they do:
Physics-based foundation models for CAD optimization.
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HQ: San Francisco, CA, United States
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AI for quantitative trading
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HQ: San Francisco, CA, United States
What they do:
Turn maps into data
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HQ: San Francisco, CA, United States
What they do:
Self learning computer use agent for developers
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HQ: San Francisco, CA, United States
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Privileged Access Management for AI Agents
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HQ: New York, NY, United States
What they do:
AI Grading for Teachers
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HQ: New York, NY, United States
What they do:
Run open models as fast as your hardware allows
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HQ: San Francisco, CA, United States
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AI-native ERP for food wholesalers
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What they do:
AI video editor
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HQ: San Francisco, CA, United States
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The continuous oversight engine for clinical trials
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HQ: San Francisco, CA, United States
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Building tiny frontier AI models that run on edge devices
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HQ: San Francisco, CA, United States
What they do:
The boring stuff, handled. Everything else, supercharged.
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HQ: San Francisco, CA, United States
What they do:
The agentic debugger for AI systems
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HQ: San Francisco, CA, United States
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The growth OS for plaintiff-side law firms
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HQ: New York, NY, United States