What they do:
Autonomous IT Delivery
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HQ: San Francisco, CA, United States
Y Combinator Summer 2026 Startups
This list has 230 startups and was last updated on Oct 15, 2026. 41 of them are hiring right now. Biggest hubs: San Francisco (185), New York (12), and Los Angeles (6). Largest teams: Isengard Industries Inc, Sunflower, and Care GP. Latest round: Mireye raised $1.01M (Sep 30, 2026).
230 startupsPage 3 of 7
What they do:
AI that turns any camera to an autonomous worker with real-time vision
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HQ: San Francisco, CA, United States
What they do:
Autonomous offensive security agents. The best defense is offense
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HQ: San Francisco, CA, United States
What they do:
The BlackRock of collectibles
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HQ: San Francisco, CA, United States
What they do:
Autonomous AI defense system for cyber attack
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HQ: San Francisco, CA, United States
What they do:
OpenRouter for Voice AI: one API, every call on the best speech model
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HQ: San Francisco, CA, United States
What they do:
Building Products and Datasets for Frontier Models
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HQ: San Francisco, CA, United States
What they do:
We turn waste gases into supply-secure chemicals
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HQ: Chicago, IL, United States
What they do:
Nervous System for Physical AI
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HQ: San Francisco, CA, United States
What they do:
Modernizing Chip Manufacturing Infrastructure
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HQ: Ann Arbor, MI, United States
What they do:
Building drone swarms that hunt hidden enemies.
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HQ: San Francisco, CA, United States
What they do:
AI-native accounting firm.
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What they do:
Robots for waste manipulation
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HQ: Zürich, Switzerland
What they do:
AI cybersecurity for financial institutions' digital assets
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What they do:
AI-native procurement services for the physical economy
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HQ: San Francisco, CA, United States
What they do:
Least cost routing system to reduce 70%+ token spend
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HQ: San Francisco, CA, United States
What they do:
AI chips for ultra-fast training and inference
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HQ: San Francisco, CA, United States
What they do:
Frontier grows scalable biological brains as an ML training substrate
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HQ: London, United Kingdom
What they do:
Evals for humans
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HQ: San Francisco, CA, United States
What they do:
24/7 Personal Health & Longevity Companion
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HQ: San Francisco, CA, United States
What they do:
Platform + FDEs that rebuild enterprises agent-first
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HQ: San Francisco, CA, United States
What they do:
Extrapolative AI to unlock First-in-Class drugs
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HQ: San Francisco, CA, United States
What they do:
AI-native pharma company
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HQ: San Francisco, CA, United States
What they do:
agents for the rest of us
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HQ: San Francisco, CA, United States
What they do:
We help lawyers start and scale AI-native law firms.
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HQ: San Francisco, CA, United States
What they do:
USA-made magnetics for robotics and defense.
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HQ: Boston, MA, United States
What they do:
The AI-Native Decision Layer for Health Insurance
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HQ: Providence, RI, United States
What they do:
The AI-native contact center
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HQ: San Francisco, CA, United States
What they do:
Watch and create anime
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HQ: San Francisco, CA, United States
What they do:
The market behind AI hardware.
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HQ: San Francisco, CA, United States
What they do:
Building a neutral, sovereign alternative to Starlink
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HQ: San Francisco, CA, United States
What they do:
Making chemicals 100,000x faster
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HQ: San Francisco, CA, United States
What they do:
Reliable and safe data engineering and data science agents
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HQ: San Francisco, CA, United States
What they do:
Reliable infrastructure to build, deploy and manage real-world robots.
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HQ: Denver, CO, United States
What they do:
Organizing company knowledge
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HQ: San Francisco, CA, United States
What they do:
Infrastructure for building and scaling AI-native businesses.
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HQ: San Francisco, CA, United States