What they do:
The AI-native radiology practice
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HQ: San Francisco, CA, United States
Y Combinator Summer 2026 Startups
This list has 230 startups and was last updated on Oct 15, 2026. 41 of them are hiring right now. Biggest hubs: San Francisco (185), New York (12), and Los Angeles (6). Largest teams: Isengard Industries Inc, Sunflower, and Care GP. Latest round: Mireye raised $1.01M (Sep 30, 2026).
230 startupsPage 6 of 7
What they do:
The Bloomberg of Loans
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HQ: San Francisco, CA, United States
What they do:
Hotels that run themselves
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HQ: San Francisco, CA, United States
What they do:
The AI Operating System for Auto Shops.
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HQ: San Francisco, CA, United States
What they do:
Training company-specific models that approve AI actions.
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HQ: San Francisco, CA, United States
What they do:
AI Brokers for Industrial Trade
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HQ: San Francisco, CA, United States
What they do:
Robots that learn on the job
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HQ: San Francisco, CA, United States
What they do:
Helping startups win gov contracts
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HQ: San Francisco, CA, United States
What they do:
AI agents for compliance at institutional trading firms
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HQ: San Francisco, CA, United States
What they do:
Multiplayer workspace for agents and humans
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HQ: San Francisco, CA, United States
What they do:
Distributed, hardware-agnostic AI inference
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HQ: San Francisco, CA, United States
What they do:
Foundational infrastructure for Physical AI
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HQ: San Francisco, CA, United States
What they do:
We make silicon on the Moon, to power everything in space.
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HQ: Los Angeles, CA, United States
What they do:
Autonomous rovers to make the ‘Google Maps’ of underground utilities
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HQ: San Francisco, CA, United States
What they do:
Duolingo for learning anything
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HQ: San Francisco, CA, United States
What they do:
Automatic Diagnosis & Fix for Industrial Automation Cells
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HQ: San Francisco, CA, United States
What they do:
Deploying robots to replace workers in hazardous spaces
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HQ: San Francisco, CA, United States
What they do:
The frontier data platform for aligned health and biological AI
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HQ: London, United Kingdom
What they do:
AI tools for the chips your AI runs on
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HQ: San Francisco, CA, United States
What they do:
Floating nuclear powered data centers at sea.
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HQ: San Francisco, CA, United States
What they do:
The biggest crowdsourced benchmark for Computer-Use
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HQ: San Francisco, CA, United States
What they do:
Open source AI gateway that turns your traffic into better models
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HQ: San Francisco, CA, United States
What they do:
AI agent that manages manufacturing operations over text
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HQ: San Francisco, CA, United States
What they do:
Robots to maintain and assemble data centers
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HQ: San Francisco, CA, United States
What they do:
The Git forge for the next hundred billion commits
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HQ: San Francisco, CA, United States
What they do:
AI-native sales agents that run marketplaces
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HQ: San Francisco, CA, United States
What they do:
High performance coding agents
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HQ: San Francisco, CA, United States
What they do:
The AI gateway for cheaper, faster, permissioned agents.
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HQ: San Francisco, CA, United States
What they do:
AWS for Agents
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HQ: San Francisco, CA, United States
What they do:
On-device Knowledge Graph engine for Enterprise Software
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HQ: San Francisco, CA, United States
What they do:
Vaccines for any cancer or infection in weeks.
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HQ: San Francisco, CA, United States
What they do:
Managed Agents API
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HQ: San Francisco, CA, United States
What they do:
Connect your agents to the stock market
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HQ: New York, NY, United States
What they do:
The open source tool gateway
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HQ: San Francisco, CA, United States
What they do:
AI that finds and fixes OS-level vulnerabilities across device fleets
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HQ: San Francisco, CA, United States
What they do:
Combining open-source AI models for better answers at lower cost
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HQ: San Francisco, CA, United States