What they do:
UI building blocks for the agentic internet
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HQ: San Francisco, CA, United States
Y Combinator Winter 2026 Startups
This list has 198 startups and was last updated on Oct 15, 2026. 64 of them are hiring right now. Biggest hubs: San Francisco (133), New York (20), and London (8). Largest teams: Human Archive, Pocket, and General Legal. Latest round: Beyond Reach Labs raised $10M (Oct 6, 2026).
198 startupsPage 4 of 6
What they do:
Logistics infrastructure to modernize healthcare operations
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HQ: Washington, DC, United States
What they do:
Anyone can create real games with AI
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HQ: San Francisco, CA, United States
What they do:
Technology to detect and track small drones
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HQ: London, United Kingdom
What they do:
Financial infrastructure for the agent economy
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HQ: San Francisco, CA, United States
What they do:
Foundation models for planning orthopedic surgery
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HQ: San Francisco, CA, United States
What they do:
LLM context compression for better accuracy
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HQ: San Francisco, CA, United States
What they do:
Unified prediction markets trading platform
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HQ: San Francisco, CA, United States
What they do:
Energy independent data centers with solar and repurposed batteries.
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What they do:
AI production engineer for regulated industries
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HQ: San Francisco, CA, United States
What they do:
Work with agents that already know you
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HQ: San Francisco, CA, United States
What they do:
AI Agents for Government Affairs
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HQ: San Francisco, CA, United States
What they do:
Frontier AI Defenses for Social Engineering Attacks
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HQ: San Francisco, CA, United States
What they do:
Evals, RL environments and training data for creative tasks
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HQ: San Francisco, CA, United States
What they do:
Intelligence for cultural institutions
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HQ: San Francisco, CA, United States
What they do:
Multi-chain deposit and payment infrastructure
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HQ: New York, NY, United States
What they do:
Software for enterprise energy procurement.
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What they do:
AI Takeoffs for Electrical
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HQ: New York, NY, United States
What they do:
iMessage revenue channel for DTC brands that brings customers back
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HQ: San Francisco, CA, United States
What they do:
Everything on anyone.
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HQ: San Francisco, CA, United States
What they do:
Building the best venue for private markets exposure.
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HQ: Los Angeles, CA, United States
What they do:
The OS for data quality across any stack
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HQ: San Francisco, CA, United States
What they do:
The control plane for AI agents.
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HQ: San Francisco, CA, United States
What they do:
Self-tuning search for products and files
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HQ: San Francisco, CA, United States
What they do:
Fast Physics Simulations for Rapid Design and Real Time Control
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HQ: San Francisco, CA, United States
What they do:
Autonomous OS for healthcare
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HQ: San Francisco, CA, United States
What they do:
Use Claude Code at 47% less cost in one line of installation.
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HQ: San Francisco, CA, United States
What they do:
AI that automatically improves products from user behavior
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HQ: San Francisco, CA, United States
What they do:
Your own chef at home
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What they do:
An AI Copilot for Trading Desks
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HQ: New York, NY, United States
What they do:
Claude Code for Mechanical Engineers
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HQ: San Francisco, CA, United States
What they do:
Datadog for Agent Reliability
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HQ: San Francisco, CA, United States
What they do:
Real time intelligence for law enforcement & security teams.
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HQ: San Francisco, CA, United States
What they do:
Detect what AI can automate for your team
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HQ: San Francisco, CA, United States
What they do:
Multimodal foundation models to predict uncollected patient biology
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HQ: San Francisco, CA, United States
What they do:
AI Employees for Primary Care
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HQ: San Francisco, CA, United States