What they do:
The user infrastructure platform
Quick facts:
HQ: San Francisco, CA, United States
Top Cloud Infrastructure Startups
This list has 493 startups and was last updated on Oct 15, 2026. 123 of them are hiring right now. Biggest hubs: San Francisco (302), New York (44), and London (16). Largest teams: Fivetran, PagerDuty, and Firebase. Latest round: Salience Labs raised $125M (Oct 14, 2026).
Survival statistics →452 open roles →
493 startupsPage 6 of 14
Zettascale Computing
Hiring
What they do:
Chips for frontier AI
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HQ: San Francisco, CA, United States
What they do:
The Localization Engineering Platform
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HQ: San Francisco, CA, United States
Unsiloed AI
Hiring
What they do:
API for parsing multimodal unstructured data
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HQ: San Francisco, CA, United States
Lemma
Hiring
What they do:
Production Monitoring for AI agents
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HQ: San Francisco, CA, United States
Cumulus Labs
Hiring
What they do:
The Fastest Multimodal Inference OS
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HQ: San Francisco, CA, United States
Salus
Hiring
What they do:
Guardrails to validate your agent's actions before they execute
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HQ: San Francisco, CA, United States
Orthogonal
Hiring
What they do:
Agentic Payments for APIs
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HQ: San Francisco, CA, United States
Reason Machines
Hiring
What they do:
Reason Machines builds Reason Agent, the autonomous software engineer…
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HQ: San Francisco, CA, United States
Uno Wallet
Hiring
What they do:
The AI mobile wallet that replaces Apple Pay
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HQ: San Francisco, CA, United States
Parasma
Hiring
What they do:
Replacing GPUs with human brain cells
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HQ: San Francisco, CA, United States
Edviro
Hiring
What they do:
AI That Operates Energy Infrastructure
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HQ: San Francisco, CA, United States
Workers IO
Hiring
What they do:
Simulation Environments for Verifying Mission Critical Software
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HQ: San Francisco, CA, United States
What they do:
World's fastest and most optimal route optimization engine
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HQ: Ontario, CA, United States
What they do:
Frontier models and agents you can learn from, audit, and steer.
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HQ: San Francisco, CA, United States
What they do:
Autonomously scaling environments
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HQ: San Francisco, CA, United States
What they do:
The fastest & most scalable graph-vector database on the market
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HQ: London, United Kingdom
What they do:
Expert STEM reasoning data for frontier AI labs.
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HQ: San Francisco, CA, United States
What they do:
Your agents should never make the same mistake twice.
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HQ: San Francisco, CA, United States
Limrun
Hiring
What they do:
Extend cloud sandboxes with iOS, Android and more
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HQ: San Francisco, CA, United States
What they do:
The agent-native serverless cloud
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HQ: San Francisco, CA, United States
What they do:
We give AI agents realtime web context via API
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HQ: San Francisco, CA, United States
What they do:
Open source agent generation framework
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HQ: San Francisco, CA, United States
QuestDB
Hiring
What they do:
Data platform for mission-critical real-time workloads
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HQ: London, United Kingdom
YC S20Early stage
What they do:
Building the next generation of visual media
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HQ: New York, NY, United States
What they do:
The complete production quality platform. AI-powered E2E testing,…
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HQ: Limerick, Ireland
What they do:
Bare-metal access to Brazil's Open Finance and Pix systems
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What they do:
Account abstraction wallets as a service
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HQ: Los Angeles, CA, United States
What they do:
Unified Hardware Control and Data Processing Software
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HQ: Denver, CO, United States
What they do:
The most powerful sandboxes for AI Agents
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HQ: San Francisco, CA, United States
What they do:
Encrypted AI with verifiable privacy
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HQ: San Francisco, CA, United States
Relling
Hiring
What they do:
deploying the first billion robots for manufacturing
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HQ: San Francisco, CA, United States
YC S25Early stage
What they do:
API for unlimited, durable, real-time streams
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HQ: San Francisco, CA, United States
What they do:
Monitoring and learning layer for long-running agents
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AgentPhone
Hiring
What they do:
Phone Numbers for AI Agents
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HQ: San Francisco, CA, United States
YC X26Early stage
What they do:
Earned intelligence for every company
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HQ: San Francisco, CA, United States