What they do:
Security for agents that self-improves
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HQ: San Francisco, CA, United States
Top Cybersecurity Startups in San Francisco
This list has 125 startups and was last updated on Oct 15, 2026. 34 of them are hiring right now. Largest teams: Vanta, TRM Labs, and Teleport. Latest round: ZeroPath raised $7.03M (Mar 23, 2026).
125 startupsPage 3 of 4
What they do:
Your personal context, securely portable across every AI app.
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HQ: San Francisco, CA, United States
What they do:
CrowdStrike for AI Agents
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HQ: San Francisco, CA, United States
What they do:
The world's frontier hacker of AI agents.
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HQ: San Francisco, CA, United States
What they do:
Training company-specific models that approve AI actions.
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HQ: San Francisco, CA, United States
What they do:
Agentic AI Security and Governance
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HQ: San Francisco, CA, United States
What they do:
The Authorization Layer for AI Agents
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HQ: San Francisco, CA, United States
What they do:
AI that finds and fixes OS-level vulnerabilities across device fleets
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HQ: San Francisco, CA, United States
What they do:
Catch wrong LLM answers before your customers do
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HQ: San Francisco, CA, United States
What they do:
Always-on AI security engineer
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HQ: San Francisco, CA, United States
What they do:
We make Privacy Software for SMBs.
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HQ: San Francisco, CA, United States
Sqreen
Acquired
What they do:
Sqreen is the application security platform for the modern enterprise
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HQ: San Francisco, CA, United States
Proxy
Acquired
What they do:
Smart ring digital wallet
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HQ: San Francisco, CA, United States
Cognito
Acquired
What they do:
Frictionless, modern identity verification that starts with just a…
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HQ: San Francisco, CA, United States
Authy
Acquired
What they do:
Authy is a Two-Factor Authentication platform for developers
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HQ: San Francisco, CA, United States
SafeBase
Acquired
What they do:
Trust Center platform that scales customer security reviews
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HQ: San Francisco, CA, United States
Optery
Acquired
What they do:
Opt out software that removes your private info from the internet
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HQ: San Francisco, CA, United States
AeroFS
Acquired
What they do:
Secure Enterprise Collaboration.
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HQ: San Francisco, CA, United States
Berbix
Acquired
What they do:
Convert more verified users. Instantly & accurately validate user IDs.
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HQ: San Francisco, CA, United States
Clickfacts
Acquired
What they do:
ClickFacts is a Malware Software Solutions company for buyers and sellers of online media. Its automated plug and play malware discovery solution tests online…
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HQ: San Francisco, CA, United States
Kuna Systems
Acquired
What they do:
We're making a smart, front door camera with intercom that lets you…
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HQ: San Francisco, CA, United States
Final
Acquired
What they do:
A credit card that drastically reduces payment fraud and gives…
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HQ: San Francisco, CA, United States
Smyte
Acquired
What they do:
Smyte stops bad actors on social networks and marketplaces.
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HQ: San Francisco, CA, United States
Templarbit
Acquired
What they do:
Protecting applications from malicious activity
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HQ: San Francisco, CA, United States
Foxpass
Acquired
What they do:
Making enterprise security practices available for all companies.
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HQ: San Francisco, CA, United States
Vectrix
Acquired
What they do:
Scan your SaaS apps and instantly identify security issues
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HQ: San Francisco, CA, United States
Telivy
Acquired
What they do:
Automate your cyber security risk assessments
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HQ: San Francisco, CA, United States
Keyri
Acquired
What they do:
Secure fraud prevention and authentication platform for developers
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HQ: San Francisco, CA, United States
EdgeBit
Acquired
What they do:
Autofix your software dependencies
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HQ: San Francisco, CA, United States
Meldium
Acquired
What they do:
Simple password & identity management for teams. Acquired by LogMeIn…
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HQ: San Francisco, CA, United States
Cryptoseal
Acquired
What they do:
Server key management, VPN as a Service, Privacy VPN. Sold to…
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HQ: San Francisco, CA, United States
CyberFend
Acquired
What they do:
Cyberfend delivers robust, real-time web and mobile security by…
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HQ: San Francisco, CA, United States
Fabric
Acquired
What they do:
Fabric is a personal location-based journal that catalogs experiences…
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HQ: San Francisco, CA, United States
Bouncer
Acquired
What they do:
SDK for scanning and verifying credit cards and photo IDs in mobile…
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HQ: San Francisco, CA, United States
Fuzzbuzz
Acquired
What they do:
Fuzzing as a Service
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HQ: San Francisco, CA, United States
YC W19Early stage
ThinAir
Shut down
What they do:
Intelligent data security for teams
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HQ: San Francisco, CA, United States