DoorDash
HiringPublic
What they do:
Restaurant delivery.
Quick facts:
HQ: San Francisco, CA, United States
Top Deep Tech Startups in San Francisco
This list has 704 startups and was last updated on Oct 15, 2026. 180 of them are hiring right now. Largest teams: DoorDash, GrubMarket, and Instacart. Latest round: Aikido Technologies raised $1.72M (Oct 8, 2026).
704 startupsPage 1 of 20
What they do:
AI-powered technology enabler and digital transformer of American…
Quick facts:
HQ: San Francisco, CA, United States
Instacart
HiringPublic
What they do:
Marketplace for grocery delivery and pickup
Quick facts:
HQ: San Francisco, CA, United States
Flexport
Hiring
What they do:
Platform for global logistics.
Quick facts:
HQ: San Francisco, CA, United States
Presto
Public
What they do:
Digital meets physical for big chain restaurants
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Tech-powered women's wellness.
Quick facts:
HQ: San Francisco, CA, United States
Momentus
Public
What they do:
The space infrastructure services company
Quick facts:
HQ: San Francisco, CA, United States
Rigetti Computing
Public
What they do:
Quantum coherent supercomputing.
Quick facts:
HQ: San Francisco, CA, United States
Oklo
Public
What they do:
Emission free, always on power from advanced fission power plants.
Quick facts:
HQ: San Francisco, CA, United States
Pardes Biosciences
Public
What they do:
We break viruses
Quick facts:
HQ: San Francisco, CA, United States
Astranis
Hiring
What they do:
Advanced satellites for high orbits.
Quick facts:
HQ: San Francisco, CA, United States
Embark Trucks
Public
What they do:
Self-driving semi trucks.
Quick facts:
HQ: San Francisco, CA, United States
Handle
Hiring
What they do:
Simplifying Payments and Compliance for Construction Suppliers
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Building the Operating System for B&M Retail using Deep Learning
Quick facts:
HQ: San Francisco, CA, United States
Mashgin
Hiring
What they do:
Self-Checkout using Computer Vision.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Artificial intelligence for drug discovery.
Quick facts:
HQ: San Francisco, CA, United States
Funding:
$19.8M · Equity · Mar 2026
Gridware
Hiring
What they do:
Protecting the grid today, preparing the grid for tomorrow
Quick facts:
HQ: San Francisco, CA, United States
Multiply Labs
Hiring
What they do:
Robotic production capacity for the pharma manufacturing industry
Quick facts:
HQ: San Francisco, CA, United States
Funding:
$75M · Series B · Oct 2026
Community Phone Company
Hiring
What they do:
The phone that gives families peace of mind about aging parents
Quick facts:
HQ: San Francisco, CA, United States
Human Archive
Hiring
What they do:
Physical AI data lab
Quick facts:
HQ: San Francisco, CA, United States
What they do:
We build cities for people, not cars.
Quick facts:
HQ: San Francisco, CA, United States
Ridecell
Hiring
What they do:
World's Leading Fleet Intelligence Platform
Quick facts:
HQ: San Francisco, CA, United States
Broccoli AI
Hiring
What they do:
AI-native operating system for home service businesses
Quick facts:
HQ: San Francisco, CA, United States
HappyRobot
Hiring
What they do:
Intelligence that runs your operations.
Quick facts:
HQ: San Francisco, CA, United States
AtoB
Hiring
What they do:
Modernizing global transportation payments.
Quick facts:
HQ: San Francisco, CA, United States
VergeSense
Hiring
What they do:
AI-Powered Building Management
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Autonomous electric airplanes
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HQ: San Francisco, CA, United States
What they do:
Next-generation DNA synthesis using enzymes
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HQ: San Francisco, CA, United States
What they do:
Shef is a Marketplace for Homemade Food
Quick facts:
HQ: San Francisco, CA, United States
BeGo
Hiring
What they do:
BeGo Connects cargo shippers with truck suppliers in Mexico and US
Quick facts:
HQ: San Francisco, CA, United States
Ready
Hiring
What they do:
Collaborative platform for optimizing regulated utilities such as…
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HQ: San Francisco, CA, United States
Shepherd
Hiring
What they do:
Modernizing commercial insurance
Quick facts:
HQ: San Francisco, CA, United States
Cambio
Hiring
What they do:
AI-native commercial real estate operations
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Cheese and dairy products from plant-derived dairy proteins
Quick facts:
HQ: San Francisco, CA, United States
Astro Mechanica
Hiring
What they do:
Supersonics for the new Jet Age
Quick facts:
HQ: San Francisco, CA, United States
Verge Genomics
Hiring
What they do:
We use human data and AI to develop better drugs faster.
Quick facts:
HQ: San Francisco, CA, United States
Questions and answers
How many startups are on this list?
There are 704 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
180 of them are hiring right now, including DoorDash, Instacart, and Flexport.
Which of them have the largest teams?
By team size: DoorDash (8,600 employees), GrubMarket (4,548 employees), and Instacart (3,000 employees).
Which of them raised money recently?
Latest rounds: Aikido Technologies — $1.72M Equity (Oct 2026), Multiply Labs — $75M Series B (Oct 2026), and Complete Robot — $1M Equity (Jun 2026).