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What they do:
Replacing orthodontic braces with our clear aligner and software
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HQ: San Francisco, CA, United States
Startups Hiring Now in the United States
This list has 1,190 startups and was last updated on Oct 15, 2026. Biggest hubs: San Francisco (784), New York (242), and Los Angeles (39). Largest teams: DoorDash, Stripe, and EquipmentShare. Latest round: Sante raised $15M (Oct 7, 2026).
1,190 startupsPage 11 of 34
What they do:
Platform that allows anyone to create and monetize video games.
Quick facts:
HQ: San Francisco, CA, United States
Aqua
Hiring
What they do:
The AI-Native Turnkey Alternative Investment Platform (TAIP)
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HQ: New York, NY, United States
222
Hiring
What they do:
the AI social facilitator for offline human to human interactions
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HQ: New York, NY, United States
Respan
Hiring
What they do:
Self-driving observability, evals, and gateway for AI agents
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HQ: San Francisco, CA, United States
Canix
Hiring
What they do:
Canix makes it easy to get and stay compliant as a cannabis business.
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HQ: San Francisco, CA, United States
Blissway
Hiring
What they do:
The tolling industry’s prime tech infrastructure
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HQ: Denver, CO, United States
Datrics
Hiring
What they do:
Generative AI Healthcare Coding Automation
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HQ: San Francisco, CA, United States
Entangl
Hiring
What they do:
Find & resolve issues in data center engineering & operations using AI
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HQ: San Francisco, CA, United States
Tandem
Hiring
What they do:
AI-native office leasing broker
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HQ: San Francisco, CA, United States
Pulse
Hiring
What they do:
Production-grade unstructured document extraction
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HQ: San Francisco, CA, United States
Kingdom
Hiring
What they do:
Clinically-validated ingredients from natural microbes
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HQ: New York, NY, United States
IOMETE
Hiring
What they do:
Self-hosted data lakehouse platform
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HQ: San Francisco, CA, United States
Strada
Hiring
What they do:
AI agents that run insurance operations
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HQ: San Francisco, CA, United States
New Story
Hiring
What they do:
We pioneer solutions to end the global housing crisis by empowering…
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HQ: Atlanta, GA, United States
Castle
Hiring
What they do:
Block bots & bad behavior
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HQ: San Francisco, CA, United States
Nestor
Hiring
What they do:
Skills-based talent management solutions for a dynamic workforce.
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HQ: San Francisco, CA, United States
Mutiny
Hiring
What they do:
Your AI agent for creating anything customer-facing, in minutes.
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HQ: New York, NY, United States
Axel Travel
Hiring
What they do:
AI agent that saves you money on travel
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HQ: Seattle, WA, United States
Accord
Hiring
What they do:
The Revenue Excellence Platform
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HQ: San Francisco, CA, United States
Handoff
Hiring
What they do:
AI estimator & agent for remodelers.
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HQ: Austin, TX, United States
Swif.ai
Hiring
What they do:
Manage every device. Govern every AI agent.
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HQ: San Francisco, CA, United States
What they do:
AI-native Robotics
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HQ: Boston, MA, United States
Runway
Hiring
What they do:
Easier and more reliable mobile app releases for teams.
Quick facts:
HQ: New York, NY, United States
Serif Health
Hiring
What they do:
Healthcare Price Transparency APIs and Data Products
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HQ: Los Angeles, CA, United States
Replo
Hiring
What they do:
Sell anything
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HQ: San Francisco, CA, United States
Parallel Bio
Hiring
What they do:
Using the immune system to cure disease
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HQ: San Francisco, CA, United States
OneSchema
Hiring
What they do:
The AI Cowork for big data
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HQ: San Francisco, CA, United States
Gym Class
Hiring
What they do:
Connecting the world by simulating it
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HQ: San Francisco, CA, United States
Medplum
Hiring
What they do:
API first electronic health record (EHR) that is open source
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HQ: San Francisco, CA, United States
Pasito
Hiring
What they do:
AI agents for insurance and benefits
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HQ: New York, NY, United States
HOMLI
Hiring
What they do:
Sell your home without brokers
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HQ: New York, NY, United States
Axle
Hiring
What they do:
AI-native clearinghouse for insurance
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HQ: New York, NY, United States
loopfour
Hiring
What they do:
Workflow automation, without AI hallucinations.
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HQ: San Francisco, CA, United States
Vector
Hiring
What they do:
Advertising for the new internet
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HQ: Boston, MA, United States
LiteLLM
Hiring
What they do:
Call every LLM API like it's OpenAI [100+ LLMs]
Quick facts:
HQ: San Francisco, CA, United States