
Sweetspot
What they do:
AI for Government Contracting.
Quick facts:
HQ: New York, NY, United States
This list has 1,491 startups and was last updated on Oct 15, 2026. Biggest hubs: San Francisco (784), New York (242), and London (57). Largest teams: DoorDash, Stripe, and EquipmentShare. Latest round: HyLight raised €13M (Oct 12, 2026).

What they do:
AI for Government Contracting.
Quick facts:
HQ: New York, NY, United States

What they do:
AI agents for fintech risk and compliance operations
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HQ: London, United Kingdom

What they do:
The modern distributor for grocers.
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HQ: New York, NY, United States

What they do:
AI-Native CPQ & Billing for Modern Pricing Models
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HQ: London, United Kingdom

What they do:
POS & operating system that makes liquor stores more money
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HQ: New York, NY, United States

What they do:
Live intelligence for biopharma teams.
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HQ: Boston, MA, United States

What they do:
AI agents for risk, compliance, and safety
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HQ: San Francisco, CA, United States

What they do:
AI research lab automating all of investing
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HQ: San Francisco, CA, United States

What they do:
The unified context layer for enterprise data
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HQ: San Francisco, CA, United States

What they do:
Foundation Model for the Brain
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HQ: New York, NY, United States

What they do:
Transparent, AI-powered healthcare TPA.
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HQ: San Francisco, CA, United States

What they do:
Simulation & Evaluation that scales voice and chat AI agents
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HQ: San Francisco, CA, United States

What they do:
The Memory layer for AI Agents
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HQ: San Francisco, CA, United States

What they do:
Complete QA platform for voice agents
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HQ: San Francisco, CA, United States

What they do:
AI call centers
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What they do:
Vanta for carbon compliance
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HQ: Denver, CO, United States

What they do:
Automated AI data integrations for roll-ups
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HQ: New York, NY, United States

What they do:
AI Co-Pilot for Chemical Process Optimization
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HQ: Cambridge, United Kingdom

What they do:
AI Broker for Tariff Refunds
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HQ: San Francisco, CA, United States

What they do:
Data for audio AI
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HQ: San Francisco, CA, United States

What they do:
GPUs for Agents
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HQ: San Francisco, CA, United States

What they do:
The OS for hospital workforce management
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HQ: New York, NY, United States

What they do:
Custom Parts, Manufactured in America 🇺🇸
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HQ: San Francisco, CA, United States

What they do:
USDC-Smart Neobank for Latinos.
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HQ: San Francisco, CA, United States

What they do:
Automate circuit board design using AI
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HQ: New York, NY, United States

What they do:
Faster healthcare payments
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HQ: San Francisco, CA, United States

What they do:
The deterministic layer for frontier intelligence
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HQ: San Francisco, CA, United States

What they do:
AI-powered Patient Identification for Clinical Trials
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HQ: Austin, TX, United States

What they do:
High Thrust Space Vehicles for Satellite Defense
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HQ: Los Angeles, CA, United States

What they do:
Making humanoids dexterous enough to thread a needle
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HQ: San Francisco, CA, United States

What they do:
Computational Law
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HQ: London, United Kingdom

What they do:
Build autonomous AI agents for enterprise systems
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HQ: San Francisco, CA, United States

What they do:
Test, monitor, and improve your voice and chat AI agents
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HQ: San Francisco, CA, United States

What they do:
Autonomous security testing for web apps, APIs, cloud, and AI systems
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What they do:
AI Mobile App Quality Assurance Tester
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HQ: San Francisco, CA, United States

What they do:
Voice data for AI
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HQ: San Francisco, CA, United States