What they do:
AI for ASIC Design Verification
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HQ: San Francisco, CA, United States
Top Manufacturing Startups
This list has 486 startups and was last updated on Oct 15, 2026. 109 of them are hiring right now. Biggest hubs: San Francisco (223), New York (26), and Los Angeles (22). Largest teams: Relativity Space, Ginkgo Bioworks, and Gecko Robotics. Latest round: Scimplify raised $25M (Oct 15, 2026).
Survival statistics →220 open roles →
486 startupsPage 6 of 14
What they do:
Automating airport baggage handling with robots.
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HQ: San Francisco, CA, United States
YC S24Early stage
What they do:
Humanoid robots that do your chores for the price of an iPhone!
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HQ: London, United Kingdom
Partcl
Hiring
What they do:
Design a chip in minutes
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HQ: San Francisco, CA, United States
YC X25Early stage
What they do:
AI-powered robotics for scientific lab automation.
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HQ: San Francisco, CA, United States
What they do:
chrt is a logistics platform for time-critical shipping
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HQ: Los Angeles, CA, United States
What they do:
The GD&T Analysis Platform for Engineering Drawings
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HQ: San Francisco, CA, United States
What they do:
A new kind of camera that can see through walls.
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HQ: San Francisco, CA, United States
What they do:
The first wearable that reads your emotions to enhance your EQ.
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HQ: San Francisco, CA, United States
What they do:
The AI-native trading company: factory prices, delivered, one number
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HQ: San Francisco, CA, United States
What they do:
The most capable American-made humanoid robot for $1,688
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HQ: San Francisco, CA, United States
What they do:
Metal manufacturing, faster, cheaper, and more versatile.
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HQ: Boston, MA, United States
Operon
Hiring
What they do:
Agentic data layer for manufacturing & process industries.
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HQ: San Francisco, CA, United States
YC S26Early stage
Lamb Labs
Hiring
What they do:
Lightning fast chips with hardcoded AI models
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
Synvivia applies chemical control over cell behavior
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HQ: San Francisco, CA, United States
What they do:
Shiru leverages ML to create proteins to feed the world sustainably.
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HQ: San Francisco, CA, United States
What they do:
We make bacteria and plants that clean up pollution.
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HQ: San Francisco, CA, United States
What they do:
Next-generation biocides for sustainable agriculture at scale
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HQ: New York, NY, United States
What they do:
Enzyme design models.
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HQ: San Francisco, CA, United States
What they do:
Applied research lab for hardware design
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HQ: San Francisco, CA, United States
What they do:
AI that turns any camera to an autonomous worker with real-time vision
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HQ: San Francisco, CA, United States
What they do:
Annotations for robotics data
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HQ: San Francisco, CA, United States
What they do:
Nervous System for Physical AI
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HQ: San Francisco, CA, United States
What they do:
Modernizing Chip Manufacturing Infrastructure
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HQ: Ann Arbor, MI, United States
What they do:
Robots for waste manipulation
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HQ: Zürich, Switzerland
What they do:
AI-native procurement services for the physical economy
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HQ: San Francisco, CA, United States
What they do:
Robots for high skilled labor powering AI infrastructure
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HQ: San Francisco, CA, United States
What they do:
Real-time cloud inference for robotics.
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HQ: San Francisco, CA, United States
What they do:
Enable robots to operate safely in the real world.
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HQ: San Francisco, CA, United States
What they do:
Skyscrape makes temperature-responsive insulation
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HQ: Portland, OR, United States
What they do:
Using DNA to store data.
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HQ: Boston, MA, United States
What they do:
The Data Platform for Mission‑Critical Systems
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HQ: San Francisco, CA, United States
What they do:
AI chips for ultra-fast training and inference
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HQ: San Francisco, CA, United States
What they do:
Foundation Model for Chemical Manufacturing
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HQ: San Francisco, CA, United States
What they do:
Batteries and solar for $0 upfront to help businesses save money
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HQ: San Francisco, CA, United States
What they do:
An AI-powered test and debug platform for chip developers
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HQ: New York, NY, United States