What they do:
Physics-based foundation models for CAD optimization.
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HQ: San Francisco, CA, United States
Top Manufacturing Startups
This list has 486 startups and was last updated on Oct 15, 2026. 109 of them are hiring right now. Biggest hubs: San Francisco (223), New York (26), and Los Angeles (22). Largest teams: Relativity Space, Ginkgo Bioworks, and Gecko Robotics. Latest round: Scimplify raised $25M (Oct 15, 2026).
Survival statistics →220 open roles →
486 startupsPage 8 of 14
What they do:
Building tiny frontier AI models that run on edge devices
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HQ: San Francisco, CA, United States
What they do:
Next generation robot deployer
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HQ: New York, NY, United States
What they do:
AI-Native Data Center Engineering
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HQ: San Francisco, CA, United States
What they do:
Waymo for excavators
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HQ: San Francisco, CA, United States
What they do:
AI-native ERP for manufacturers
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HQ: San Francisco, CA, United States
What they do:
Your own chef at home
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What they do:
The robot workforce for infrastructure
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HQ: San Francisco, CA, United States
What they do:
Automating dexterous tasks in warehouses with AI-powered robots
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HQ: San Francisco, CA, United States
What they do:
AI that runs factories.
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HQ: San Francisco, CA, United States
What they do:
Research lab building the most robotic household in the world
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HQ: San Francisco, CA, United States
What they do:
Humanoid robot platform for builders.
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HQ: San Francisco, CA, United States
What they do:
Control lab instruments with natural language.
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HQ: San Francisco, CA, United States
What they do:
Deployment infrastructure for Physical AI
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HQ: San Francisco, CA, United States
What they do:
AI Native Sourcing Broker For Overseas Manufacturing
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HQ: San Francisco, CA, United States
What they do:
Robots for vehicle maintenance.
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HQ: San Francisco, CA, United States
What they do:
Making Diamond Semiconductors
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HQ: San Francisco, CA, United States
What they do:
Real-world RL environments for robotics models
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HQ: San Francisco, CA, United States
What they do:
Making Defense Manufacturing Faster and Cheaper
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HQ: New York, NY, United States
What they do:
OpenClaw for manufacturers
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HQ: San Francisco, CA, United States
What they do:
We are a multi-strategy trading firm that trains AI traders.
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HQ: San Francisco, CA, United States
What they do:
Drop-in robotic labor that works on Day 1
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HQ: Los Angeles, CA, United States
What they do:
Industrial Controllers built for AI
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HQ: Los Angeles, CA, United States
What they do:
Virtual Reality for Training Robots
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HQ: San Francisco, CA, United States
What they do:
Robots that learn on the job
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HQ: San Francisco, CA, United States
What they do:
Foundational infrastructure for Physical AI
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HQ: San Francisco, CA, United States
What they do:
We make silicon on the Moon, to power everything in space.
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HQ: Los Angeles, CA, United States
What they do:
Automatic Diagnosis & Fix for Industrial Automation Cells
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HQ: San Francisco, CA, United States
What they do:
Deploying robots to replace workers in hazardous spaces
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HQ: San Francisco, CA, United States
What they do:
AI tools for the chips your AI runs on
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HQ: San Francisco, CA, United States
What they do:
A factory for small and specialized video reasoning models
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What they do:
Agents running industrial enterprises from back office to shop floor
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HQ: San Francisco, CA, United States
What they do:
Quick-turn, purpose-built motors & actuators for all
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HQ: Los Angeles, CA, United States
What they do:
The generalist robot deployment company.
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HQ: San Francisco, CA, United States
What they do:
Self-improving inference workstation
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HQ: Milan, Italy
What they do:
On Demand CNC Prototyping
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HQ: San Francisco, CA, United States