What they do:
End-to-end Simulation for Defense Autonomy
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HQ: San Francisco, CA, United States
Top Space & Defense Startups in San Francisco
This list has 47 startups and was last updated on Oct 15, 2026. 20 of them are hiring right now. Largest teams: Astranis, Momentus, and Pyka.
47 startupsPage 2 of 2
What they do:
Delivering AI-powered situational awareness in tactical environments.
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HQ: San Francisco, CA, United States
What they do:
Foundation models for 24/7 Earth Observation
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HQ: San Francisco, CA, United States
What they do:
The hardware-agnostic operating system for drone defense
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HQ: San Francisco, CA, United States
What they do:
Deploying robots to replace workers in hazardous spaces
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HQ: San Francisco, CA, United States
What they do:
Precision navigation for UAVs operating without GPS.
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HQ: San Francisco, CA, United States
What they do:
Tankless Dive Gear - Breath Autonomy at Sea, Land & Space
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HQ: San Francisco, CA, United States
What they do:
Autopilot for Flight Operations
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HQ: San Francisco, CA, United States
YC S26Early stage
What they do:
AI-guided ballistic missiles, cheap enough to field in numbers that…
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HQ: San Francisco, CA, United States
YC F26Early stage
SpaceRyde
Shut down
What they do:
The Rocket Network: Sustainable & On-Demand Delivery Anywhere in Space
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HQ: San Francisco, CA, United States
Bagaveev Corporation
Shut down
What they do:
Launch small satellites
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HQ: San Francisco, CA, United States