What they do:
Control lab instruments with natural language.
Quick facts:
HQ: San Francisco, CA, United States
Top Automation Startups
This list has 98 startups and was last updated on Oct 15, 2026. 31 of them are hiring right now. Biggest hubs: San Francisco (58), New York (13), and London (3). Largest teams: Zapier, Ginkgo Bioworks, and Lob. Latest round: CircuitHub raised $25.5M (May 13, 2026).
98 startupsPage 3 of 3
What they do:
The AI Workforce for Biopharma
Quick facts:
HQ: San Francisco, CA, United States
What they do:
We make law firms AI-native.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
OpenClaw for manufacturers
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Industrial Controllers built for AI
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
AI Brokers for Industrial Trade
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Next-generation agent operating system
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Automate on-call at agent-scale.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
FollowUpThen is an email-based personal assistant that sends you…
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Specialized agents for real work
Quick facts:
HQ: Los Angeles, CA, United States
What they do:
Open-source agentic security automation platform
Quick facts:
HQ: New York, NY, United States
YC W24Early stage
What they do:
Reimagining how Machines Learn
Quick facts:
HQ: San Francisco, CA, United States
YC W25Early stage
What they do:
AI-native back-office for banks and fintechs
Quick facts:
HQ: San Francisco, CA, United States
YC S26Early stage
Quick facts:
HQ: Cincinnati, OH, United States
StackAI
Acquired
What they do:
The Enterprise AI Transformation Platform
Quick facts:
HQ: San Francisco, CA, United States
Saleswhale
Acquired
What they do:
Saleswhale is an automated sales assistant that follows up with your…
Quick facts:
HQ: Singapore
Clara Labs
Acquired
What they do:
Clara is a human-in-the-loop assistant that helps automate repetitive…
Quick facts:
HQ: San Francisco, CA, United States
Chute
Acquired
What they do:
Discover the photos and videos people are taking of your brand or…
Quick facts:
HQ: San Francisco, CA, United States
Cohere
Acquired
What they do:
Support automation that's actually intelligent
Quick facts:
HQ: New York, NY, United States
Laudspeaker
Acquired
What they do:
Open source mobile marketing platform. Alternative to appcues /…
Quick facts:
HQ: San Francisco, CA, United States
Autotab
Acquired
What they do:
AI agents reliable enough to do real work
Quick facts:
HQ: San Francisco, CA, United States
RoboTire
Shut down
What they do:
Robotire is automating vehicle maintenance for today and future…
Quick facts:
HQ: Plymouth, MI, United States
Integration Labs
Shut down
What they do:
The Unified API for Business Financial Data
Quick facts:
Mystro
Shut down
What they do:
Mystro is an app that makes rideshare drivers up to 30% more money by…
Quick facts:
HQ: San Francisco, CA, United States
Sidenote
Shut down
What they do:
Meeting follow-up, automated
Quick facts:
HQ: San Francisco, CA, United States
crmCopilot
Shut down
What they do:
Give Salesforce the AI upgrade it deserves
Quick facts:
HQ: San Francisco, CA, United States