
Coinbase
What they do:
Buy, sell, and manage cryptocurrencies.
Quick facts:
HQ: Los Angeles, CA, United States
This list has 94 startups and was last updated on Oct 15, 2026. 16 of them are hiring right now. Biggest hubs: San Francisco (26), New York (14), and Los Angeles (6). Largest teams: Coinbase, Protocol Labs, and Quicknode.

What they do:
Buy, sell, and manage cryptocurrencies.
Quick facts:
HQ: Los Angeles, CA, United States

What they do:
Protocol Labs makes internet protocols: IPFS, Filecoin, and more.
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HQ: San Francisco, CA, United States

What they do:
Tools & infra to build and scale high-quality blockchain applications.
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HQ: Miami, FL, United States

What they do:
The global financial platform for affluent consumers in the Americas.
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HQ: London, United Kingdom

What they do:
Security auditing for Web3
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HQ: San Francisco, CA, United States
What they do:
The gold standard in cryptocurrency portfolio tracking and taxes
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HQ: San Francisco, CA, United States

What they do:
This isn't just a marketplace; we're shaping the future of digital…
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HQ: New York, NY, United States

What they do:
Crypto-currency trading platform.
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HQ: Los Angeles, CA, United States

What they do:
The Notabene platform is the trust layer for global money movement.
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HQ: New York, NY, United States

What they do:
Your global dollar account powered by stablecoins
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HQ: New York, NY, United States

What they do:
The AI-native financial platform for enterprises
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HQ: Manaus, Brazil

What they do:
Crypto Exchange and Payment API Gateway
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HQ: Buenos Aires, Argentina

What they do:
Dollar banking for people in Latin America
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What they do:
Cryptocurrency infrastructure for Africa.
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HQ: London, United Kingdom

What they do:
SpruceID lets users control their data across the web.
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HQ: New York, NY, United States

What they do:
Global neobank for emerging markets
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HQ: San Francisco, CA, United States

What they do:
Open-source, design centric software for interacting with blockchains
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HQ: New York, NY, United States

What they do:
Decentralised broadband connectivity.
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What they do:
AI driven payment rails for emerging market banks.
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HQ: San Francisco, CA, United States

What they do:
The global neo-bank for contractors and freelancers
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HQ: Buenos Aires, Argentina

What they do:
Payments & Loyalty Infrastructure
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What they do:
All things money, with better money
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What they do:
Infrastructure powering stablecoin and digital finance
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What they do:
Brex for D2C Brands and Content Creators in Indonesia
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What they do:
Request is a payment request technology & an ecosystem of apps
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What they do:
Coinrule Automates Your Crypto and Stock Investments
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HQ: London, United Kingdom

What they do:
India's largest crypto investing paltform
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What they do:
The Global Dollar App for Brazil
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What they do:
The Trading Terminal For Crypto Traders
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HQ: Austin, TX, United States

What they do:
A social streaming platform powered by creators and fans
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HQ: Los Angeles, CA, United States

What they do:
Seamless Fiat Payments for Web3
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HQ: Singapore

What they do:
LATAM’s largest stablecoin FX and liquidity provider
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HQ: Mexico City, Mexico

What they do:
Agentic Finance for your Life and Business
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HQ: Remote

What they do:
Stackup helps businesses manage their crypto assets.
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HQ: Los Angeles, CA, United States

What they do:
Stablecoin API for global payments
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HQ: San Francisco, CA, United States

What they do:
Cross border Payments infrastructure for internet businesses and…
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There are 94 startups on this list, last updated on Oct 15, 2026.
16 of them are hiring right now, including Quicknode, ARQ, and CoinTracker.
By team size: Coinbase (6,112 employees), Protocol Labs (130 employees), and Quicknode (115 employees).
The biggest hubs are San Francisco (26), New York (14), and Los Angeles (6).