What they do:
Empowering every doctor and every patient to participate in research
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HQ: New York, NY, United States
Top Enterprise Software Startups
This list has 136 startups and was last updated on Oct 15, 2026. 50 of them are hiring right now. Biggest hubs: San Francisco (76), New York (17), and Toronto (4). Largest teams: Checkr, Leena AI, and CareRev. Latest round: Momentic raised $18.6M (Jan 27, 2026).
136 startupsPage 3 of 4
What they do:
AI for ASIC Design Verification
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HQ: San Francisco, CA, United States
What they do:
Faster, more profitable background checks with AI
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HQ: Los Angeles, CA, United States
Adaptional
Hiring
What they do:
AI-powered insurance claims review
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HQ: San Francisco, CA, United States
YC S25Early stage
What they do:
AI agents for E2E testing across mobile & web
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HQ: San Francisco, CA, United States
Soren
Hiring
What they do:
The AI Transformation Company
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HQ: San Francisco, CA, United States
YC F25Early stage
What they do:
Help business find and discover AI solutions
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HQ: Seattle, WA, United States
What they do:
On-demand labour that's actually good
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What they do:
AI Assistant for Excel
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HQ: New York, NY, United States
What they do:
QA agents that write tests 10x faster with zero maintenance
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HQ: San Francisco, CA, United States
What they do:
Streamlining Data Capture to Report Creation for Heavy Industries
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HQ: San Francisco, CA, United States
What they do:
The AI workforce for People and Finance teams
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What they do:
Autonomous IT Delivery
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HQ: San Francisco, CA, United States
What they do:
Let agents talk to your customers
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HQ: San Francisco, CA, United States
What they do:
AI agents that run onboarding, adoption, and renewals
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HQ: San Francisco, CA, United States
What they do:
Your AI Partner for SAP Development
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HQ: San Francisco, CA, United States
What they do:
A Reliable AI Frontend Engineer
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HQ: San Francisco, CA, United States
What they do:
A new kind of ERP system for factories
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HQ: Singapore
What they do:
Struct keeps prod running
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HQ: San Francisco, CA, United States
What they do:
Cursor for Email
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HQ: San Francisco, CA, United States
What they do:
Context-aware orchestration between humans and AI.
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HQ: London, United Kingdom
What they do:
AI production engineer for regulated industries
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HQ: San Francisco, CA, United States
What they do:
Reliable and safe data engineering and data science agents
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HQ: San Francisco, CA, United States
What they do:
Model Agnostic AI coworker in Slack
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HQ: San Francisco, CA, United States
What they do:
Continuous optimization for AI agents
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HQ: San Francisco, CA, United States
What they do:
We help livestream sellers get more sales.
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HQ: Singapore
What they do:
Building your AI coworkers for any team, workflow, or industry.
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HQ: Seattle, WA, United States
What they do:
AI voice agents for healthcare operational calls
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HQ: New York, NY, United States
What they do:
Simple, LLM-first translation and internationalization for software
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HQ: San Francisco, CA, United States
What they do:
Help Institutional Investors manage, track & query their Excel models
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HQ: New York, NY, United States
What they do:
The data gateway for agents.
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HQ: San Francisco, CA, United States
What they do:
AI agents for web testing
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HQ: San Francisco, CA, United States
What they do:
The AI workspace for software implementations
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HQ: San Francisco, CA, United States
What they do:
Self learning computer use agent for developers
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HQ: San Francisco, CA, United States
What they do:
We help non-technical teams build AI agents without engineers
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HQ: Brussels, Belgium
What they do:
Your software should build itself.
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