What they do:
Hosting platform for software you can't afford to have hacked
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HQ: George Town, Cayman Islands
Top Infrastructure Startups
This list has 417 startups and was last updated on Oct 15, 2026. 111 of them are hiring right now. Biggest hubs: San Francisco (271), New York (38), and London (10). Largest teams: Fivetran, Firebase, and Heroku. Latest round: Supabase raised $150M (Oct 2, 2026).
417 startupsPage 6 of 12
What they do:
Context layer for enterprise AI surveying employees with voice agents
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HQ: San Francisco, CA, United States
What they do:
Serverless Infrastructure Platform for AI
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HQ: New York, NY, United States
What they do:
Palantir for Web3
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HQ: New York, NY, United States
What they do:
Build and host internal tools
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HQ: Ashburn, VA, United States
What they do:
We sell GPUs.
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HQ: San Francisco, CA, United States
What they do:
The cheapest, fastest inference cloud
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HQ: San Francisco, CA, United States
What they do:
The AIOps Agent for ML Teams
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HQ: Seattle, WA, United States
What they do:
The World's Largest Video Library
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HQ: San Francisco, CA, United States
What they do:
AI that turns any camera to an autonomous worker with real-time vision
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HQ: San Francisco, CA, United States
What they do:
Company Brain.
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HQ: San Francisco, CA, United States
What they do:
Unlock wasted GPU capacity.
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HQ: London, United Kingdom
What they do:
OpenRouter for Voice AI: one API, every call on the best speech model
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HQ: San Francisco, CA, United States
What they do:
Unmanned cargo airplanes
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HQ: Los Angeles, CA, United States
What they do:
Real-time cloud inference for robotics.
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HQ: San Francisco, CA, United States
What they do:
Super fast, unblockable browser infra for agents
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HQ: San Francisco, CA, United States
What they do:
A Nouns DAO governance client
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What they do:
The easiest way to use AWS for agents and humans
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HQ: Dayton, OH, United States
What they do:
Models that keep learning
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HQ: London, United Kingdom
What they do:
Deploy serverless without rewriting code
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HQ: San Francisco, CA, United States
What they do:
All-in-one platform to create AI agents with your private knowledge
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HQ: San Francisco, CA, United States
What they do:
Infrastructure for managing GPU clusters for training/serving.
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HQ: San Francisco, CA, United States
What they do:
Infuse knowledge into language models with just 10 samples
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HQ: San Francisco, CA, United States
What they do:
AI-powered Infrastructure as Code PR reviews
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What they do:
Config Management for Robotics
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HQ: San Francisco, CA, United States
What they do:
Ship self-hosted software with Distr
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What they do:
The COLD Task Framework
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HQ: San Francisco, CA, United States
What they do:
Lossless web data.
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HQ: San Francisco, CA, United States
What they do:
Turn employees' AI skills into shared company infrastructure
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HQ: San Francisco, CA, United States
What they do:
Stripe for telephony
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HQ: Lehi, UT, United States
What they do:
Continual Learning for Agents
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HQ: San Francisco, CA, United States
What they do:
Open Source React.js Library for AI Chat
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HQ: San Francisco, CA, United States
What they do:
Specialized AI for Critical Industries
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HQ: San Francisco, CA, United States
What they do:
Production infrastructure on autopilot
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HQ: San Francisco, CA, United States
What they do:
Digital Twins of humans
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HQ: New York, NY, United States
What they do:
LLM context compression for better accuracy
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HQ: San Francisco, CA, United States