What they do:
AI drug discovery platform for neurotherapeutics
Quick facts:
HQ: San Francisco, CA, United States
Funding:
$2.16M · Options · Feb 2026
Top Neurotechnology Startups
This list has 20 startups and was last updated on Oct 15, 2026. 3 of them are hiring right now. Biggest hubs: San Francisco (10), New York (2), and Portland (2). Largest teams: Craniometrix, BIOS Health, and Actipulse Neuroscience. Latest round: Exin Therapeutics raised $2.16M (Feb 10, 2026).
20 startups
Craniometrix
Hiring
What they do:
Using AI to help dementia patients age at home
Quick facts:
HQ: New York, NY, United States
What they do:
Neural interfaces to understand and use nerve data in medicine.
Quick facts:
HQ: Cambridge, United Kingdom
What they do:
Bringing non-invasive brain stimulation from the hospital to the home
Quick facts:
HQ: Mexico City, Mexico
What they do:
Brain Longevity
Quick facts:
HQ: San Francisco, CA, United States
Piramidal
Hiring
What they do:
Foundation Model for the Brain
Quick facts:
HQ: New York, NY, United States
What they do:
Human whole body end-of-life preservation for later revival.
Quick facts:
HQ: Portland, OR, United States
What they do:
Programmable biology company for psychoactive effect design
Quick facts:
HQ: San Francisco, CA, United States
Parasma
Hiring
What they do:
Replacing GPUs with human brain cells
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Utilizing monogenic disorders to inform and solve highly complex…
Quick facts:
HQ: Portland, OR, United States
What they do:
High-precision, closed-loop neuromodulation devices
Quick facts:
HQ: Boston, MA, United States
What they do:
The neural engine for autonomous robots
Quick facts:
HQ: St. Louis, MO, United States
What they do:
Motor cortex for physical AI
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Neurostimulation implant to restore hearing & speech understanding
Quick facts:
HQ: San Francisco, CA, United States
What they do:
A consumer brain-computer interface you can map to anything.
Quick facts:
HQ: San Francisco, CA, United States
Rain Neuromorphics
Acquired
What they do:
We build artificial intelligence processors inspired by the brain.
Quick facts:
HQ: San Francisco, CA, United States
Voyage Biomedical
Acquired
What they do:
Using cooling to end brain damage during stroke.
Quick facts:
HQ: San Francisco, CA, United States
MindPortal
Shut down
What they do:
Thought-to-Language AI Models
Quick facts:
HQ: London, United Kingdom
Prophecy Sciences
Shut down
What they do:
Predicting workplace performance through neuroscience
Quick facts:
HQ: San Francisco, CA, United States
SpringWit
Shut down
What they do:
Brain health and awareness
Quick facts:
YC S14Early stage
Questions and answers
How many startups are on this list?
There are 20 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
3 of them are hiring right now, including Craniometrix, Piramidal, and Parasma.
Which of them have the largest teams?
By team size: Craniometrix (64 employees), BIOS Health (45 employees), and Actipulse Neuroscience (38 employees).
Which of them raised money recently?
Latest rounds: Exin Therapeutics — $2.16M Options (Feb 2026).
Where are they based?
The biggest hubs are San Francisco (10), New York (2), and Portland (2).