What they do:
Conversational Voice and Multimodal AI built with Open Source
Quick facts:
HQ: San Francisco, CA, United States
Top AI Agent Startups in San Francisco
This list has 151 startups and was last updated on Oct 15, 2026. 55 of them are hiring right now. Largest teams: Daily, Broccoli AI, and Weekend (fmr. Volley). Latest round: Copilot Labs, Inc. \ DE raised $21.2M (Jan 23, 2026).
151 startupsPage 1 of 5
Broccoli AI
Hiring
What they do:
AI-native operating system for home service businesses
Quick facts:
HQ: San Francisco, CA, United States
Weekend (fmr. Volley)
Hiring
What they do:
AI games and entertainment on TV
Quick facts:
HQ: San Francisco, CA, United States
HappyRobot
Hiring
What they do:
Intelligence that runs your operations.
Quick facts:
HQ: San Francisco, CA, United States
BIK
Hiring
What they do:
Agentic AI CRM for ecommerce
Quick facts:
HQ: San Francisco, CA, United States
Artisan
Hiring
What they do:
AI employees that take on real work, starting with sales
Quick facts:
HQ: San Francisco, CA, United States
Domu Technology Inc.
Hiring
What they do:
AI Agents for collections
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Platform to easily create chatbots to engage with audiences on…
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-powered content creation infrastructure for apps
Quick facts:
HQ: San Francisco, CA, United States
Hyperbound
Hiring
What they do:
Revenue Activation Platform
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Replika is an AI friend that you can talk to designed to make you…
Quick facts:
HQ: San Francisco, CA, United States
loopfour
Hiring
What they do:
Workflow automation, without AI hallucinations.
Quick facts:
HQ: San Francisco, CA, United States
Inkeep
Hiring
What they do:
Build AI Agent teammates and automations in code or no-code
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI Applied Research
Quick facts:
HQ: San Francisco, CA, United States
Kastle
Hiring
What they do:
AI employee for consumer lending
Quick facts:
HQ: San Francisco, CA, United States
Toothy AI
Hiring
What they do:
AI for insurance verification & billing at dental clinics
Quick facts:
HQ: San Francisco, CA, United States
Leaping AI
Hiring
What they do:
AI voice and texting agents
Quick facts:
HQ: San Francisco, CA, United States
Zep AI
Hiring
What they do:
The unified context layer for enterprise data
Quick facts:
HQ: San Francisco, CA, United States
Hamming AI
Hiring
What they do:
Complete QA platform for voice agents
Quick facts:
HQ: San Francisco, CA, United States
Bluejay
Hiring
What they do:
Test, monitor, and improve your voice and chat AI agents
Quick facts:
HQ: San Francisco, CA, United States
Lance
Hiring
What they do:
AI Agents That Run Hotel Operations.
Quick facts:
HQ: San Francisco, CA, United States
ego
Hiring
What they do:
AI applied research lab building synthetic sapience; human-like AI
Quick facts:
HQ: San Francisco, CA, United States
Berry
Hiring
What they do:
Scale customer success and onboarding with AI
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Voice AI platform purpose-built for contact centers.
Quick facts:
HQ: San Francisco, CA, United States
Callab AI
Hiring
What they do:
AI voice agents for on-prem telephony stack.
Quick facts:
HQ: San Francisco, CA, United States
Runtime
Hiring
What they do:
The AI agent harness for payment teams
Quick facts:
HQ: San Francisco, CA, United States
Flair Labs
Hiring
What they do:
AI workforce for mortgage
Quick facts:
HQ: San Francisco, CA, United States
Surface Labs
Hiring
What they do:
Building the AI-powered marketing ops platform that turns website…
Quick facts:
HQ: San Francisco, CA, United States
Apten
Hiring
What they do:
Omnichannel AI agents that engage leads across SMS, voice, and email
Quick facts:
HQ: San Francisco, CA, United States
VideoGen
Hiring
What they do:
Create professional videos in minutes with AI, online or via API
Quick facts:
HQ: San Francisco, CA, United States
Dodo
Hiring
What they do:
AI agents that handle communications for clinics
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Build an AI support agent that securely uses all your tools
Quick facts:
HQ: San Francisco, CA, United States
Dench.com
Hiring
What they do:
Workspace for your AI Agents, Build any Workflow.
Quick facts:
HQ: San Francisco, CA, United States
Capy
Hiring
What they do:
The IDE for the parallel age
Quick facts:
HQ: San Francisco, CA, United States
Solidroad
Hiring
What they do:
AI agents for CX teams, starting with training and QA.
Quick facts:
HQ: San Francisco, CA, United States
item
Hiring
What they do:
The AI-Native CRM that works for you
Quick facts:
HQ: San Francisco, CA, United States
Questions and answers
How many startups are on this list?
There are 151 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
55 of them are hiring right now, including Broccoli AI, Weekend (fmr. Volley), and HappyRobot.
Which of them have the largest teams?
By team size: Daily (126 employees), Broccoli AI (85 employees), and Weekend (fmr. Volley) (80 employees).
Which of them raised money recently?
Latest rounds: Copilot Labs, Inc. \ DE — $21.2M Equity (Jan 2026).