What they do:
Real-world sandboxes to test and train AI agents
Quick facts:
HQ: San Francisco, CA, United States
Top AI Agent Startups in San Francisco
This list has 151 startups and was last updated on Oct 15, 2026. 55 of them are hiring right now. Largest teams: Daily, Broccoli AI, and Weekend (fmr. Volley). Latest round: Copilot Labs, Inc. \ DE raised $21.2M (Jan 23, 2026).
151 startupsPage 3 of 5
What they do:
Context layer for enterprise AI surveying employees with voice agents
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-Native Restaurant POS
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI-powered product assistance for modern software teams
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The Open-Source Alternative to Claude Managed Agents
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The full-stack AI financial audit firm
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Let agents talk to your customers
Quick facts:
HQ: San Francisco, CA, United States
What they do:
OpenRouter for Voice AI: one API, every call on the best speech model
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI Fitness Coach
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The AI Assistant for Gmail
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Test, monitor, and improve your voice agents
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Open Source React.js Library for AI Chat
Quick facts:
HQ: San Francisco, CA, United States
What they do:
A personal EA in your iMessage
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Cursor for Email
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI employees trained on your firm's workflows.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Expressive conversational AI
Quick facts:
HQ: San Francisco, CA, United States
What they do:
UI building blocks for the agentic internet
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Marketplace for AI agents to hire humans.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The agentic OS for medical labs
Quick facts:
HQ: San Francisco, CA, United States
What they do:
A personal or team assistant that works while you sleep
Quick facts:
HQ: San Francisco, CA, United States
What they do:
agents for the rest of us
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Organizing company knowledge
Quick facts:
HQ: San Francisco, CA, United States
What they do:
An AI bracelet that remembers your day and acts before you ask.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Conversational AI assistants using your knowledge
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI coding copilot engineered for performance
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Your self-generating, self-maintaining code knowledge base.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI assisted documentation for PT/OT/SLP
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Build a website by chatting with AI
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI for humans
Quick facts:
HQ: San Francisco, CA, United States
What they do:
The personal AI agent that keeps up with your work and life.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
the AI coding app for thinking.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AI agents for insurance claims
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Open source agentic BI for founders
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Your email assistant because you deserve a better morning
Quick facts:
HQ: San Francisco, CA, United States
What they do:
Orca lets you build, discover, and play Minecraft games with friends.
Quick facts:
HQ: San Francisco, CA, United States
What they do:
AWS for AI Agents
Quick facts:
HQ: San Francisco, CA, United States