What they do:
Let agents talk to your customers
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HQ: San Francisco, CA, United States
Top AI & Data Startups in California
This list has 1,550 startups and was last updated on Oct 15, 2026. 481 of them are hiring right now. Biggest hubs: San Francisco (1,471), Los Angeles (51), and San Diego (5). Largest teams: Cruise, Relativity Space, and Fivetran. Latest round: Safi Analytics raised $22.4M (Oct 14, 2026).
1,550 startupsPage 22 of 44
What they do:
AI-Native Investor Relations
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HQ: San Francisco, CA, United States
What they do:
Autonomous offensive security agents. The best defense is offense
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HQ: San Francisco, CA, United States
What they do:
Autonomous AI defense system for cyber attack
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HQ: San Francisco, CA, United States
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OpenRouter for Voice AI: one API, every call on the best speech model
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HQ: San Francisco, CA, United States
What they do:
Building Products and Datasets for Frontier Models
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HQ: San Francisco, CA, United States
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Least cost routing system to reduce 70%+ token spend
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HQ: San Francisco, CA, United States
What they do:
Unifying Global Private Credit
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HQ: San Francisco, CA, United States
What they do:
Turn Your Taste Into Hires
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HQ: San Francisco, CA, United States
What they do:
AI agents that run onboarding, adoption, and renewals
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HQ: San Francisco, CA, United States
What they do:
Robots for high skilled labor powering AI infrastructure
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HQ: San Francisco, CA, United States
What they do:
Real-time cloud inference for robotics.
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HQ: San Francisco, CA, United States
What they do:
Enable robots to operate safely in the real world.
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HQ: San Francisco, CA, United States
What they do:
Analytics, built for the trades.
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HQ: San Francisco, CA, United States
What they do:
Growing micro-organs to find new drugs
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HQ: San Francisco, CA, United States
What they do:
A search technology that actually finds what you’re looking for.
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HQ: San Francisco, CA, United States
What they do:
Deploy serverless without rewriting code
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HQ: San Francisco, CA, United States
What they do:
AI-first user research platform
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HQ: San Francisco, CA, United States
What they do:
Platform to automate manual back-office work
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HQ: San Francisco, CA, United States
What they do:
Find the best leads with custom intent signals
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HQ: San Francisco, CA, United States
What they do:
Your AI Partner for SAP Development
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HQ: San Francisco, CA, United States
What they do:
The AI Platform for Medical Education
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HQ: San Francisco, CA, United States
What they do:
The AI platform for CRE investment teams
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HQ: San Francisco, CA, United States
What they do:
The API for LLM tool use
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HQ: San Francisco, CA, United States
What they do:
AI chips for ultra-fast training and inference
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HQ: San Francisco, CA, United States
What they do:
All-in-one platform to create AI agents with your private knowledge
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HQ: San Francisco, CA, United States
What they do:
Build games at the speed of thought
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HQ: San Francisco, CA, United States
What they do:
Infrastructure for managing GPU clusters for training/serving.
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HQ: San Francisco, CA, United States
What they do:
RankAI grows your website on autopilot
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HQ: San Francisco, CA, United States
What they do:
Infuse knowledge into language models with just 10 samples
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HQ: San Francisco, CA, United States
What they do:
AI back office for food product quality teams
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HQ: Los Angeles, CA, United States
What they do:
AI Fitness Coach
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HQ: San Francisco, CA, United States
What they do:
People search powered by AI
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HQ: San Francisco, CA, United States
What they do:
AI Website platform that grows revenue automatically
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HQ: San Francisco, CA, United States
What they do:
Foundation Model for Chemical Manufacturing
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HQ: San Francisco, CA, United States
What they do:
Attunement turns fragmented behavioral health records into structured…
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HQ: San Francisco, CA, United States