What they do:
Menten AI designs peptide and protein therapeutics using quantum…
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HQ: San Francisco, CA, United States
Top AI & Data Startups in California
This list has 1,550 startups and was last updated on Oct 15, 2026. 481 of them are hiring right now. Biggest hubs: San Francisco (1,471), Los Angeles (51), and San Diego (5). Largest teams: Cruise, Relativity Space, and Fivetran. Latest round: Safi Analytics raised $22.4M (Oct 14, 2026).
1,550 startupsPage 26 of 44
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AI to track and analyze public policy
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HQ: San Francisco, CA, United States
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Conversational AI assistants using your knowledge
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HQ: San Francisco, CA, United States
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Sequin is building AI Voice Agents to automate collections calls for…
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HQ: San Francisco, CA, United States
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AI Search for the Next Generation
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HQ: San Francisco, CA, United States
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AI agents to build B2B datasets
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HQ: San Francisco, CA, United States
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The best AI chat you've ever used
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HQ: San Francisco, CA, United States
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Turn everyday videos into movies.
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HQ: San Francisco, CA, United States
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AI-powered engineering productivity tools
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HQ: San Francisco, CA, United States
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Your autonomous motion designer that turns every feature into a…
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HQ: San Francisco, CA, United States
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AI Diagnosis of Heart Disease
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HQ: San Francisco, CA, United States
What they do:
type text, dream video
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HQ: San Francisco, CA, United States
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AI coding copilot engineered for performance
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HQ: San Francisco, CA, United States
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Deploy Machine Learning Models with One Command
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HQ: San Francisco, CA, United States
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AI Teammates for Data Tasks
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HQ: San Francisco, CA, United States
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Your self-generating, self-maintaining code knowledge base.
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HQ: San Francisco, CA, United States
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AI assisted documentation for PT/OT/SLP
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HQ: San Francisco, CA, United States
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Automating nutrition tracking.
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HQ: San Francisco, CA, United States
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Network Intelligence for Investors
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HQ: San Francisco, CA, United States
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Building a frontier world model for power
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HQ: Los Angeles, CA, United States
What they do:
Program computers with natural language
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HQ: San Francisco, CA, United States
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Screen recorder for stunning product demo videos
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HQ: San Francisco, CA, United States
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CRM Co-Pilot for Medtech Sales
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HQ: San Francisco, CA, United States
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Build a website by chatting with AI
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HQ: San Francisco, CA, United States
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AI Agents for Enterprises
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HQ: San Francisco, CA, United States
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AI for humans
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HQ: San Francisco, CA, United States
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Observability and evaluation platform for LLM apps.
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HQ: San Francisco, CA, United States
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Automate your chargebacks with AI agents
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HQ: San Francisco, CA, United States
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orchestrate your coding agents with sudocode
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HQ: San Francisco, CA, United States
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ML to predict and prevent pregnancy complications
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HQ: San Diego, CA, United States
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Long-horizon research agents
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HQ: San Francisco, CA, United States
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The personal AI agent that keeps up with your work and life.
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HQ: San Francisco, CA, United States
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AI-native customer support platform
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HQ: San Francisco, CA, United States
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the AI coding app for thinking.
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HQ: San Francisco, CA, United States
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Voice Agents for Healthcare Operations
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HQ: San Francisco, CA, United States
What they do:
Helping Companies Deploy Email Agents in High Trust Domains
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HQ: San Francisco, CA, United States