What they do:
The AI Workforce for Biopharma
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HQ: San Francisco, CA, United States
Top AI & Data Startups in California
This list has 1,550 startups and was last updated on Oct 15, 2026. 481 of them are hiring right now. Biggest hubs: San Francisco (1,471), Los Angeles (51), and San Diego (5). Largest teams: Cruise, Relativity Space, and Fivetran. Latest round: Safi Analytics raised $22.4M (Oct 14, 2026).
1,550 startupsPage 31 of 44
What they do:
AI-native patient engagement
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HQ: San Francisco, CA, United States
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OpenRouter for Agent Tools
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HQ: San Francisco, CA, United States
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The first AI founder: a virtual human who runs his own companies.
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HQ: San Francisco, CA, United States
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AI For The Skilled Workforce
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HQ: San Francisco, CA, United States
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Effortlessly deploy cloud software factories.
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HQ: San Francisco, CA, United States
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We make law firms AI-native.
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HQ: San Francisco, CA, United States
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Your personal context, securely portable across every AI app.
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HQ: San Francisco, CA, United States
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Crafting simulations for frontier lab model training
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HQ: San Francisco, CA, United States
What they do:
The autonomous AI model factory
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HQ: San Francisco, CA, United States
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AI FDE that deploys custom AI agents into ERPs
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HQ: San Francisco, CA, United States
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Real-world RL environments for robotics models
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HQ: San Francisco, CA, United States
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Simulating Agents Running Industrial Companies
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HQ: San Francisco, CA, United States
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Accurately simulate market response at scale
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HQ: San Francisco, CA, United States
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Self-optimizing neocloud that cuts LLM costs by 100x
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HQ: San Francisco, CA, United States
What they do:
AI Agents to Make Local Gov Efficient
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HQ: San Francisco, CA, United States
What they do:
Foundation models on enterprise transaction data.
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HQ: San Francisco, CA, United States
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AI-native OS for Real Estate Brokerages
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HQ: San Francisco, CA, United States
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OpenClaw for manufacturers
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HQ: San Francisco, CA, United States
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Defining the frontier of multiplayer AI.
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HQ: San Francisco, CA, United States
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AI brain for creators that runs their social content
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HQ: Los Angeles, CA, United States
What they do:
Market for future inference capacity
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HQ: San Francisco, CA, United States
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Training the world's best AI model for quantitative finance.
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HQ: San Francisco, CA, United States
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CrowdStrike for AI Agents
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HQ: San Francisco, CA, United States
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AI Operating System for Wholesale Distribution
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HQ: San Francisco, CA, United States
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Databricks for Enterprise Codebases
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HQ: San Francisco, CA, United States
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Legora for AEC (Architecture, Engineering, & Construction) firms
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HQ: San Francisco, CA, United States
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The world's frontier hacker of AI agents.
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HQ: San Francisco, CA, United States
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Legora for commercial insurance carriers
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HQ: San Francisco, CA, United States
What they do:
AI-Native Insurance for Frontier Tech
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HQ: San Francisco, CA, United States
What they do:
Predict how market participants behave
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HQ: San Francisco, CA, United States
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Virtual Reality for Training Robots
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HQ: San Francisco, CA, United States
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AI-Native Engineering Firm designing Data Centers
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HQ: San Francisco, CA, United States
What they do:
Curing cancer. Starting with dogs.
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HQ: San Francisco, CA, United States
What they do:
We find where AI agents fail, then train better models to run them.
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HQ: San Francisco, CA, United States
What they do:
The AI-native radiology practice
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HQ: San Francisco, CA, United States