What they do:
Self-Driving CI: fast AI-native GitHub Actions runners
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HQ: San Francisco, CA, United States
Top AI & Data Startups in San Francisco
This list has 1,471 startups and was last updated on Oct 15, 2026. 463 of them are hiring right now. Largest teams: Cruise, Fivetran, and Athelas. Latest round: Safi Analytics raised $22.4M (Oct 14, 2026).
1,471 startupsPage 23 of 41
What they do:
Build and ship native Swift apps with AI
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HQ: San Francisco, CA, United States
What they do:
World's largest crowdsourced benchmark for AI-generated design
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HQ: San Francisco, CA, United States
What they do:
Cursor for Email
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HQ: San Francisco, CA, United States
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Building medical school for AI Agents
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HQ: San Francisco, CA, United States
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AI content manager that grows your company's online presence
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HQ: San Francisco, CA, United States
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AI for the physical world
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HQ: San Francisco, CA, United States
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Truckload Planning at Machine Precision
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HQ: San Francisco, CA, United States
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AI employees trained on your firm's workflows.
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HQ: San Francisco, CA, United States
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Digital transformation for real economy businesses
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HQ: San Francisco, CA, United States
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TikTok for language learning
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HQ: San Francisco, CA, United States
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Continuous AI pentesting that finds and fixes vulnerabilities
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HQ: San Francisco, CA, United States
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AI clerks that automate your payables
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HQ: San Francisco, CA, United States
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Large-scale real-world robot & human data for embodied AI
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HQ: San Francisco, CA, United States
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Expressive conversational AI
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HQ: San Francisco, CA, United States
What they do:
Team chat to command all your company's coding agents
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HQ: San Francisco, CA, United States
What they do:
Insurance risk layer for physical AI
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HQ: San Francisco, CA, United States
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Underwrite borrowers around the world in minutes
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HQ: San Francisco, CA, United States
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UI building blocks for the agentic internet
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HQ: San Francisco, CA, United States
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AI production engineer for regulated industries
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HQ: San Francisco, CA, United States
What they do:
Work with agents that already know you
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HQ: San Francisco, CA, United States
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Evals, RL environments and training data for creative tasks
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HQ: San Francisco, CA, United States
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Intelligence for cultural institutions
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HQ: San Francisco, CA, United States
What they do:
Evals for humans
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HQ: San Francisco, CA, United States
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24/7 Personal Health & Longevity Companion
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HQ: San Francisco, CA, United States
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Platform + FDEs that rebuild enterprises agent-first
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HQ: San Francisco, CA, United States
What they do:
Marketplace for AI agents to hire humans.
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HQ: San Francisco, CA, United States
What they do:
Building the Data Infrastructure layer for Physical AI.
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HQ: San Francisco, CA, United States
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Extrapolative AI to unlock First-in-Class drugs
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HQ: San Francisco, CA, United States
What they do:
AI nutrition coach in your pocket
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HQ: San Francisco, CA, United States
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The agentic OS for medical labs
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HQ: San Francisco, CA, United States
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AI-native CRO for clinical trial operations
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HQ: San Francisco, CA, United States
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Patreon for AI Originals
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HQ: San Francisco, CA, United States
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AI-native pharma company
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HQ: San Francisco, CA, United States
What they do:
A personal or team assistant that works while you sleep
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HQ: San Francisco, CA, United States
What they do:
agents for the rest of us
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HQ: San Francisco, CA, United States