What they do:
The continuous oversight engine for clinical trials
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HQ: San Francisco, CA, United States
Top AI & Data Startups in San Francisco
This list has 1,471 startups and was last updated on Oct 15, 2026. 463 of them are hiring right now. Largest teams: Cruise, Fivetran, and Athelas. Latest round: Safi Analytics raised $22.4M (Oct 14, 2026).
1,471 startupsPage 28 of 41
What they do:
Building intellectually curious AI
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HQ: San Francisco, CA, United States
What they do:
Building tiny frontier AI models that run on edge devices
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HQ: San Francisco, CA, United States
What they do:
The boring stuff, handled. Everything else, supercharged.
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HQ: San Francisco, CA, United States
What they do:
The agentic debugger for AI systems
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HQ: San Francisco, CA, United States
What they do:
The Cursor for Chip Design - Delivering Silicon-Ready Chip Designs…
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HQ: San Francisco, CA, United States
What they do:
Your personal AI Assistant
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HQ: San Francisco, CA, United States
What they do:
Turns products into CLIs and agents into customers
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HQ: San Francisco, CA, United States
What they do:
Waymo for excavators
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HQ: San Francisco, CA, United States
What they do:
Planet-scale people discovery.
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HQ: San Francisco, CA, United States
What they do:
AI-native ERP for manufacturers
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HQ: San Francisco, CA, United States
What they do:
Synthetic populations for decisions
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HQ: San Francisco, CA, United States
What they do:
Automating regulatory submissions for life sciences
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HQ: San Francisco, CA, United States
What they do:
Payment infrastructure for AI agents
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HQ: San Francisco, CA, United States
What they do:
Find what's losing you customers and money in your AI agent and fix it
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HQ: San Francisco, CA, United States
What they do:
TikTok for Sports Trading
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HQ: San Francisco, CA, United States
What they do:
The OS for data quality across any stack
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HQ: San Francisco, CA, United States
What they do:
Delivering AI-powered situational awareness in tactical environments.
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HQ: San Francisco, CA, United States
What they do:
The sensitive data redaction layer for AI
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HQ: San Francisco, CA, United States
What they do:
AI Agents for Platform Engineering
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HQ: San Francisco, CA, United States
What they do:
The control plane for AI agents.
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HQ: San Francisco, CA, United States
What they do:
A proactive desktop copilot. Clippy, but actually good.
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HQ: San Francisco, CA, United States
What they do:
AI language buddy in the games kids love
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HQ: San Francisco, CA, United States
What they do:
Self-tuning search for products and files
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HQ: San Francisco, CA, United States
What they do:
The coding agent that actually collaborates with you
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HQ: San Francisco, CA, United States
What they do:
Code and browse in the same place
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HQ: San Francisco, CA, United States
What they do:
The first platform where families can create AI cartoons in minutes
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HQ: San Francisco, CA, United States
What they do:
The first Agentic platform for Oncology
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HQ: San Francisco, CA, United States
What they do:
Use Claude Code at 47% less cost in one line of installation.
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HQ: San Francisco, CA, United States
What they do:
AI that automatically improves products from user behavior
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HQ: San Francisco, CA, United States
What they do:
Detect what AI can automate for your team
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HQ: San Francisco, CA, United States
What they do:
AI Employees for Primary Care
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HQ: San Francisco, CA, United States
What they do:
Enterprise post-training, monitoring, and continual learning platform
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HQ: San Francisco, CA, United States
What they do:
AI models that learn from experience
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HQ: San Francisco, CA, United States
What they do:
AI SRE agent that triages, coordinates, and fixes production incidents
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HQ: San Francisco, CA, United States
What they do:
AI native radars for self-driving cars
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HQ: San Francisco, CA, United States