What they do:
Enzyme design models.
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HQ: San Francisco, CA, United States
Top AI & Data Startups in the United States
This list has 2,134 startups and was last updated on Oct 15, 2026. 661 of them are hiring right now. Biggest hubs: San Francisco (1,471), New York (339), and Los Angeles (51). Largest teams: Cruise, Relativity Space, and Fivetran. Latest round: Safi Analytics raised $22.4M (Oct 14, 2026).
2,134 startupsPage 29 of 60
What they do:
Building a nervous system for the atmosphere
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HQ: San Francisco, CA, United States
What they do:
We build floating solar data centers
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HQ: San Francisco, CA, United States
What they do:
Executable healthcare contracts
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HQ: San Francisco, CA, United States
What they do:
Navigate any set of data - no matter how large - in minutes.
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HQ: New York, NY, United States
What they do:
AI Employees for Distributors
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HQ: San Francisco, CA, United States
What they do:
The Open Source Agentic Browser
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HQ: San Francisco, CA, United States
What they do:
AI Affiliate Network For Financial Companies
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HQ: San Francisco, CA, United States
What they do:
AI tutor starting with maths and science
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HQ: San Francisco, CA, United States
What they do:
Cooking something sweet and salty!
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HQ: San Francisco, CA, United States
What they do:
Foundation models to automate x-ray analysis for radiologists
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HQ: San Francisco, CA, United States
What they do:
Deep intelligence for private markets
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HQ: San Francisco, CA, United States
What they do:
Product Native Models
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HQ: San Francisco, CA, United States
What they do:
Streamlining Data Capture to Report Creation for Heavy Industries
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HQ: San Francisco, CA, United States
What they do:
Real-world company data for frontier AI
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HQ: San Francisco, CA, United States
What they do:
Your personal AI for language learning
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HQ: San Francisco, CA, United States
What they do:
We sell GPUs.
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HQ: San Francisco, CA, United States
What they do:
Applied research lab for hardware design
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HQ: San Francisco, CA, United States
What they do:
The Open-Source Alternative to Claude Managed Agents
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HQ: San Francisco, CA, United States
What they do:
The world's first AI-maximalist pharma company
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HQ: San Francisco, CA, United States
What they do:
AI powered brokerage reducing residential rental commissions in NYC…
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HQ: San Francisco, CA, United States
What they do:
Build an API to interact with any website.
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HQ: San Francisco, CA, United States
What they do:
A Foundation Model for Microbial Communities.
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HQ: San Francisco, CA, United States
What they do:
The full-stack AI financial audit firm
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HQ: San Francisco, CA, United States
What they do:
AI Voice callers for healthcare billing teams
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HQ: San Francisco, CA, United States
What they do:
Compliance that makes products ready for global markets.
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HQ: Atlanta, GA, United States
What they do:
Operational Intelligence for Global Logistics
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HQ: San Francisco, CA, United States
What they do:
The AI sales agent for CPG brands
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HQ: San Francisco, CA, United States
What they do:
AI benchmarks that measure general intelligence and inspire new ideas
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HQ: San Francisco, CA, United States
What they do:
The cheapest, fastest inference cloud
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HQ: San Francisco, CA, United States
What they do:
AI Customer Support for Fortune 500-scale enterprises
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HQ: San Francisco, CA, United States
What they do:
AI-native transformation for operations-heavy companies
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HQ: San Francisco, CA, United States
What they do:
Autonomous IT Delivery
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HQ: San Francisco, CA, United States
What they do:
AI operating system for mega-scale satellite networks.
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HQ: Seattle, WA, United States
What they do:
The World's Largest Video Library
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HQ: San Francisco, CA, United States
What they do:
AI that turns any camera to an autonomous worker with real-time vision
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HQ: San Francisco, CA, United States