What they do:
Let agents talk to your customers
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HQ: San Francisco, CA, United States
Top AI & Data Startups in the United States
This list has 2,134 startups and was last updated on Oct 15, 2026. 661 of them are hiring right now. Biggest hubs: San Francisco (1,471), New York (339), and Los Angeles (51). Largest teams: Cruise, Relativity Space, and Fivetran. Latest round: Safi Analytics raised $22.4M (Oct 14, 2026).
2,134 startupsPage 30 of 60
What they do:
AI-Native Investor Relations
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HQ: San Francisco, CA, United States
What they do:
Autonomous offensive security agents. The best defense is offense
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HQ: San Francisco, CA, United States
What they do:
Autonomous AI defense system for cyber attack
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HQ: San Francisco, CA, United States
What they do:
OpenRouter for Voice AI: one API, every call on the best speech model
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HQ: San Francisco, CA, United States
What they do:
Building Products and Datasets for Frontier Models
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HQ: San Francisco, CA, United States
What they do:
Least cost routing system to reduce 70%+ token spend
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HQ: San Francisco, CA, United States
What they do:
Unifying Global Private Credit
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HQ: San Francisco, CA, United States
What they do:
Stripe for medical billing
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HQ: Austin, TX, United States
What they do:
Turn Your Taste Into Hires
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HQ: San Francisco, CA, United States
What they do:
AI agents that run onboarding, adoption, and renewals
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HQ: San Francisco, CA, United States
What they do:
Robots for high skilled labor powering AI infrastructure
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HQ: San Francisco, CA, United States
What they do:
Real-time cloud inference for robotics.
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HQ: San Francisco, CA, United States
What they do:
Shire uses CCTV to run restaurants in real time.
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HQ: Myrtle Beach, SC, United States
What they do:
Enable robots to operate safely in the real world.
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HQ: San Francisco, CA, United States
What they do:
The neural engine for autonomous robots
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HQ: St. Louis, MO, United States
What they do:
Cursor for data analysis
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HQ: New York, NY, United States
What they do:
Analytics, built for the trades.
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HQ: San Francisco, CA, United States
What they do:
Semi-Autonomous Diagnostics for Emergent Care
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HQ: FL, United States
What they do:
Real-time sales coach for SDRs
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HQ: New York, NY, United States
What they do:
Growing micro-organs to find new drugs
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HQ: San Francisco, CA, United States
What they do:
Helping physicians select the right therapy for breast cancer patients
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HQ: Austin, TX, United States
What they do:
AI English Tutor
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HQ: New York, NY, United States
What they do:
Automatically fill empty appointment slots for beauty professionals
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HQ: Orem, UT, United States
What they do:
A search technology that actually finds what you’re looking for.
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HQ: San Francisco, CA, United States
What they do:
Deploy serverless without rewriting code
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HQ: San Francisco, CA, United States
What they do:
AI-first user research platform
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HQ: San Francisco, CA, United States
What they do:
We build tools to help humanity predict the future.
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HQ: New York, NY, United States
What they do:
Platform to automate manual back-office work
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HQ: San Francisco, CA, United States
What they do:
Automating root cause analysis with generative AI
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HQ: New York, NY, United States
What they do:
Find the best leads with custom intent signals
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HQ: San Francisco, CA, United States
What they do:
Deal Intelligence and Sales Coaching Platform
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HQ: New York, NY, United States
What they do:
Your AI Partner for SAP Development
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HQ: San Francisco, CA, United States
What they do:
The AI Platform for Medical Education
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HQ: San Francisco, CA, United States
What they do:
The AI platform for CRE investment teams
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HQ: San Francisco, CA, United States
What they do:
The API for LLM tool use
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HQ: San Francisco, CA, United States