Giga
Hiring
What they do:
AI Support Agent for Enterprises.
Quick facts:
HQ: San Francisco, CA, United States
Top AI & Data Startups in the United States
This list has 2,134 startups and was last updated on Oct 15, 2026. 661 of them are hiring right now. Biggest hubs: San Francisco (1,471), New York (339), and Los Angeles (51). Largest teams: Cruise, Relativity Space, and Fivetran. Latest round: Safi Analytics raised $22.4M (Oct 14, 2026).
2,134 startupsPage 6 of 60
What they do:
AI code review agent with complete context of your codebase
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HQ: San Francisco, CA, United States
Reducto
Hiring
What they do:
The complete agentic document platform
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HQ: San Francisco, CA, United States
Alex
Hiring
What they do:
Alex is the AI recruiter for hiring great people.
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HQ: San Francisco, CA, United States
AfterQuery
Hiring
What they do:
Applied research lab curating data solutions for foundation model…
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HQ: San Francisco, CA, United States
Auctor
Hiring
What they do:
The agentic operating system for modern system integrators.
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HQ: New York, NY, United States
Metriport
Hiring
What they do:
Healthcare data infrastructure for next generation care delivery.
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HQ: San Francisco, CA, United States
What they do:
AI that finds the right buyers and books sales meetings
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HQ: San Francisco, CA, United States
Synthio Labs
Hiring
What they do:
Agentic AI platform for Pharma GTM teams
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HQ: San Francisco, CA, United States
Topline Pro
Hiring
What they do:
Generative AI powered Shopify for home service professionals
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HQ: New York, NY, United States
Two Dots
Hiring
What they do:
AI fraud prevention and underwriting agent
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HQ: San Francisco, CA, United States
What they do:
Real-World Data for Health Innovation
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HQ: San Francisco, CA, United States
Blue Onion
Hiring
What they do:
Financial data layer for AI-powered finance and accounting
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HQ: New York, NY, United States
Uplane
Hiring
What they do:
Replace marketing agencies with AI
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HQ: San Francisco, CA, United States
What they do:
AI Super-Apps to Live Easier | The anything anytime superapps…
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HQ: Los Angeles, CA, United States
What they do:
Empowering women. Period.
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HQ: San Francisco, CA, United States
Nimble
Hiring
What they do:
Data-driven teacher hiring
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HQ: Miami, FL, United States
Assembly
Hiring
What they do:
Create remarkable client experiences
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HQ: New York, NY, United States
Alpha Vantage
Hiring
What they do:
Developer-friendly and enterprise-grade APIs for financial market…
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HQ: Boston, MA, United States
What they do:
AI customer reputation & performance management for restaurant chains.
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HQ: New York, NY, United States
What they do:
A new kind of power for finance teams
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HQ: San Francisco, CA, United States
Atomic
Hiring
What they do:
API that lets companies embed investment accounts into their services
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HQ: San Francisco, CA, United States
What they do:
AI-powered customer service for startups
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HQ: New York, NY, United States
What they do:
Git for Lawyers — now within Claude
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HQ: New York, NY, United States
Mach9
Hiring
What they do:
AI CAD Software for Civil Engineering
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HQ: San Francisco, CA, United States
What they do:
Modernizing Specialty Insurance
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HQ: New York, NY, United States
Invert
Hiring
What they do:
Data analytics software for biomanufacturing.
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HQ: San Francisco, CA, United States
Polymath Robotics
Hiring
What they do:
General Autonomy for Industrial Vehicles
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HQ: San Francisco, CA, United States
mdhub
Hiring
What they do:
AI-native operating system for behavioral health clinics.
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HQ: San Francisco, CA, United States
Ember
Hiring
What they do:
AI RCM. Increase net revenue by 16%.
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HQ: San Francisco, CA, United States
Harper
Hiring
What they do:
AI-native commercial insurance brokerage
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HQ: San Francisco, CA, United States
What they do:
The Javascript framework for building AI agents, from the Gatsby devs
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HQ: San Francisco, CA, United States
What they do:
Mass-produced AI strike systems and Counter-UAS
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HQ: San Francisco, CA, United States
What they do:
Handl converts documents (invoices, income stabs, custom forms, etc.)…
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HQ: San Francisco, CA, United States
HUD
Hiring
What they do:
Platform and marketplace for RL environments and AI data
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HQ: San Francisco, CA, United States
What they do:
Replika is an AI friend that you can talk to designed to make you…
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HQ: San Francisco, CA, United States