What they do:
Data for biomedical AI
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HQ: San Francisco, CA, United States
Top AI Startups in San Francisco
This list has 1,355 startups and was last updated on Oct 15, 2026. 443 of them are hiring right now. Largest teams: Cruise, Athelas, and Checkr. Latest round: Litewave.AI raised $200K (Oct 7, 2026).
1,355 startupsPage 21 of 38
What they do:
A Reliable AI Frontend Engineer
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HQ: San Francisco, CA, United States
What they do:
Agents for quantitative research and financial data science.
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HQ: San Francisco, CA, United States
What they do:
Legal Agent that delivers finished work
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HQ: San Francisco, CA, United States
What they do:
Automating workflows.
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HQ: San Francisco, CA, United States
What they do:
Turn employees' AI skills into shared company infrastructure
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HQ: San Francisco, CA, United States
What they do:
AI Agents for Lending Operations
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HQ: San Francisco, CA, United States
What they do:
The new American reinsurance company.
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HQ: San Francisco, CA, United States
What they do:
The Lovable & Replit killers
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HQ: San Francisco, CA, United States
What they do:
Struct keeps prod running
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HQ: San Francisco, CA, United States
What they do:
The AI Assistant for Gmail
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HQ: San Francisco, CA, United States
What they do:
AI powered debugging notebooks for incident response
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HQ: San Francisco, CA, United States
What they do:
Building AI systems that improve from experience.
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HQ: San Francisco, CA, United States
What they do:
Hire amazing engineers by seeing how they use AI
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HQ: San Francisco, CA, United States
What they do:
A foundation model for physics.
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HQ: San Francisco, CA, United States
What they do:
Fast and Data-Driven Immigration Platform
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HQ: San Francisco, CA, United States
What they do:
Protect and Grow Long-tail Revenue
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HQ: San Francisco, CA, United States
What they do:
Test, monitor, and improve your voice agents
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HQ: San Francisco, CA, United States
What they do:
Continual Learning for Agents
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HQ: San Francisco, CA, United States
What they do:
Open Source React.js Library for AI Chat
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HQ: San Francisco, CA, United States
What they do:
Custom models trained on your data
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HQ: San Francisco, CA, United States
What they do:
Creator marketing that scales like paid ads
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HQ: San Francisco, CA, United States
What they do:
AI tutor for each student.
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HQ: San Francisco, CA, United States
What they do:
We automate your entire product development lifecycle.
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HQ: San Francisco, CA, United States
What they do:
Open-source frontier models for knowledge work
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HQ: San Francisco, CA, United States
What they do:
Understand your users beyond the numbers
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HQ: San Francisco, CA, United States
What they do:
A personal EA in your iMessage
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HQ: San Francisco, CA, United States
What they do:
Specialized AI for Critical Industries
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HQ: San Francisco, CA, United States
What they do:
Automatically write and update internal docs with every code commit.
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HQ: San Francisco, CA, United States
What they do:
Self-Driving CI: fast AI-native GitHub Actions runners
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HQ: San Francisco, CA, United States
What they do:
Build and ship native Swift apps with AI
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HQ: San Francisco, CA, United States
What they do:
World's largest crowdsourced benchmark for AI-generated design
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HQ: San Francisco, CA, United States
What they do:
Cursor for Email
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HQ: San Francisco, CA, United States
What they do:
AI content manager that grows your company's online presence
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HQ: San Francisco, CA, United States
What they do:
AI for the physical world
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HQ: San Francisco, CA, United States
What they do:
Truckload Planning at Machine Precision
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HQ: San Francisco, CA, United States