Centaur
Hiring
What they do:
We Create Superior Data By Making Annotation Competitive
Quick facts:
HQ: Boston, MA, United States
Top AI Startups in Massachusetts
This list has 37 startups and was last updated on Oct 15, 2026. 6 of them are hiring right now. Largest teams: Centaur, PostEra, and Yuma AI. Latest round: SkyNexus AI raised $100K (Oct 6, 2026).
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PostEra
Hiring
What they do:
Medicinal Chemistry powered by Machine Learning
Quick facts:
HQ: Boston, MA, United States
Alpha Vantage
Hiring
What they do:
Developer-friendly and enterprise-grade APIs for financial market…
Quick facts:
HQ: Boston, MA, United States
What they do:
The AI Support Agent for Ecommerce
Quick facts:
HQ: Boston, MA, United States
What they do:
Automated tooth cutting for dentists using imaging, AI and robotics
Quick facts:
HQ: Boston, MA, United States
What they do:
AI-native Robotics
Quick facts:
HQ: Boston, MA, United States
Vector
Hiring
What they do:
Advertising for the new internet
Quick facts:
HQ: Boston, MA, United States
What they do:
Next-generation mRNA platform to solve cancer, COVID and climate.
Quick facts:
HQ: Boston, MA, United States
What they do:
Multimodal AI Platform for Modality Agnostic Drug Discovery™
Quick facts:
HQ: Boston, MA, United States
What they do:
Kernal is creating mRNA 2.0 therapies that work in specific cells
Quick facts:
HQ: Boston, MA, United States
What they do:
Agents for Accelerated Clinical Trial Design
Quick facts:
HQ: Boston, MA, United States
Maven Bio
Hiring
What they do:
Live intelligence for biopharma teams.
Quick facts:
HQ: Boston, MA, United States
What they do:
We use AI to design antibodies for intractable diseases
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HQ: Boston, MA, United States
What they do:
Recover failed subscription payments to increase retention and LTV
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HQ: Boston, MA, United States
What they do:
Create custom NLP models
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HQ: Boston, MA, United States
What they do:
Gen-AI Designed Enzymes for Pharmaceutical Innovation
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HQ: Boston, MA, United States
What they do:
coaching agents for athletes
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HQ: Boston, MA, United States
What they do:
Simulate your customers with AI agents
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HQ: Boston, MA, United States
What they do:
Robotic Training Data at Scale
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HQ: Boston, MA, United States
What they do:
Scaling Genomic AI for Embryo Selection
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HQ: Boston, MA, United States
What they do:
Robots for the inspection and maintenance of data centers
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HQ: Boston, MA, United States
What they do:
Life sciences reagents and software
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HQ: Boston, MA, United States
What they do:
The AI-Native Consumer + Plaintiff Law Firm
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HQ: Boston, MA, United States
What they do:
The fully autonomous intelligence layer in the sky.
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HQ: Boston, MA, United States
What they do:
The IDE for Tokenmaxxers
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HQ: Boston, MA, United States
What they do:
Infrastructure Cartography
Quick facts:
HQ: Boston, MA, United States
What they do:
Next-Generation Surgical Navigation and Robotics
Quick facts:
HQ: Boston, MA, United States
YC S19Early stage
What they do:
AI-controlled optical switching for AI clusters
Quick facts:
HQ: Boston, MA, United States
YC S26Early stage
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2021
Funding:
$29.7M · Equity · Jun 2026
Quick facts:
HQ: Cambridge, MA, United States
Incorporated: 2022
Funding:
$8M · Options · May 2026
Quick facts:
HQ: Needham, MA, United States
Funding:
$6.72M · Equity · Jan 2026
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2023
Funding:
$2.8M · Equity · Feb 2026
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2025
Funding:
$100K · SAFE · Oct 2026
Bytebot
Acquired
What they do:
Bytebot is the open source container for AI desktop agents.
Quick facts:
HQ: Boston, MA, United States
Reverie Labs
Shut down
What they do:
Engineering next-generation, brain-penetrant cancer therapies.
Quick facts:
HQ: Boston, MA, United States
SenpAI.GG
Shut down
What they do:
Personal gaming coach for PC gamers globally
Quick facts:
HQ: Boston, MA, United States
Questions and answers
How many startups are on this list?
There are 37 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
6 of them are hiring right now, including Centaur, PostEra, and Alpha Vantage.
Which of them have the largest teams?
By team size: Centaur (45 employees), PostEra (40 employees), and Yuma AI (26 employees).
Which of them raised money recently?
Latest rounds: SkyNexus AI — $100K SAFE (Oct 2026), Consensus NLP — $29.7M Equity (Jun 2026), and Tycho AI — $8M Options (May 2026).