What they do:
Extrapolative AI to unlock First-in-Class drugs
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HQ: San Francisco, CA, United States
Top AI Startups in the United States
This list has 1,958 startups and was last updated on Oct 15, 2026. 632 of them are hiring right now. Biggest hubs: San Francisco (1,355), New York (312), and Los Angeles (47). Largest teams: Cruise, Relativity Space, and Podium. Latest round: Agriculture Scout AI raised $425K (Oct 13, 2026).
1,958 startupsPage 32 of 55
What they do:
AI nutrition coach in your pocket
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HQ: San Francisco, CA, United States
What they do:
AI-native CRO for clinical trial operations
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HQ: San Francisco, CA, United States
What they do:
Working capital for data companies training frontier AI
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HQ: New York, NY, United States
What they do:
Patreon for AI Originals
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HQ: San Francisco, CA, United States
What they do:
AI-native pharma company
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HQ: San Francisco, CA, United States
What they do:
A personal or team assistant that works while you sleep
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HQ: San Francisco, CA, United States
What they do:
agents for the rest of us
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HQ: San Francisco, CA, United States
What they do:
We help lawyers start and scale AI-native law firms.
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HQ: San Francisco, CA, United States
What they do:
The AI-Native Decision Layer for Health Insurance
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HQ: Providence, RI, United States
What they do:
Watch and create anime
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HQ: San Francisco, CA, United States
What they do:
The market behind AI hardware.
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HQ: San Francisco, CA, United States
What they do:
Building a neutral, sovereign alternative to Starlink
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HQ: San Francisco, CA, United States
What they do:
Making chemicals 100,000x faster
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HQ: San Francisco, CA, United States
What they do:
Reliable and safe data engineering and data science agents
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HQ: San Francisco, CA, United States
What they do:
Build everyday back-office agents on one live model of your books
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HQ: San Francisco, CA, United States
What they do:
Organizing company knowledge
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HQ: San Francisco, CA, United States
What they do:
Infrastructure for building and scaling AI-native businesses.
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HQ: San Francisco, CA, United States
What they do:
AI-native test infrastructure layer for hardware companies
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HQ: San Francisco, CA, United States
What they do:
The social trading app for stocks, memes, and perps
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HQ: San Francisco, CA, United States
What they do:
Oura Ring for Skin
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HQ: San Francisco, CA, United States
What they do:
The identity and communication layer for AI agents
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HQ: San Francisco, CA, United States
What they do:
We find flaws in RL environments and evals and help you fix them.
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HQ: San Francisco, CA, United States
What they do:
Florin is an AI-native insurance company that runs autonomously
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HQ: San Francisco, CA, United States
What they do:
Internal industrial company data for frontier labs
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HQ: San Francisco, CA, United States
What they do:
Autoresearch as a service: we solve your hardest measurable problems
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HQ: San Francisco, CA, United States
What they do:
Evals for robots
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HQ: San Francisco, CA, United States
What they do:
Model Agnostic AI coworker in Slack
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HQ: San Francisco, CA, United States
What they do:
Wet lab infrastructure that turns AI experiments into training data.
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HQ: San Francisco, CA, United States
What they do:
See and control what your agents actually do
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HQ: San Francisco, CA, United States
What they do:
Predictive maintenance for power infrastructure.
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HQ: Baltimore, MD, United States
What they do:
An AI-operated logistics company.
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HQ: San Francisco, CA, United States
What they do:
Embodied Scientific Intelligence
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HQ: San Francisco, CA, United States
What they do:
An AI bracelet that remembers your day and acts before you ask.
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HQ: San Francisco, CA, United States
What they do:
Motor cortex for physical AI
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HQ: San Francisco, CA, United States
What they do:
Continuous optimization for AI agents
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HQ: San Francisco, CA, United States