What they do:
Patreon for AI Originals
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HQ: San Francisco, CA, United States
Top AI Startups
This list has 2,481 startups and was last updated on Oct 15, 2026. 746 of them are hiring right now. Biggest hubs: San Francisco (1,355), New York (312), and London (82). Largest teams: Cruise, Relativity Space, and Podium. Latest round: Scimplify raised $25M (Oct 15, 2026).
Survival statistics →2,520 open roles →
2,481 startupsPage 43 of 69
What they do:
AI-native pharma company
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HQ: San Francisco, CA, United States
What they do:
A personal or team assistant that works while you sleep
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HQ: San Francisco, CA, United States
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Roma is the to-do list that does itself
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agents for the rest of us
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HQ: San Francisco, CA, United States
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We help lawyers start and scale AI-native law firms.
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HQ: San Francisco, CA, United States
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The AI-Native Decision Layer for Health Insurance
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HQ: Providence, RI, United States
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Watch and create anime
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HQ: San Francisco, CA, United States
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The market behind AI hardware.
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HQ: San Francisco, CA, United States
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Building a neutral, sovereign alternative to Starlink
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HQ: San Francisco, CA, United States
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Making chemicals 100,000x faster
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HQ: San Francisco, CA, United States
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Reliable and safe data engineering and data science agents
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HQ: San Francisco, CA, United States
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Build everyday back-office agents on one live model of your books
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HQ: San Francisco, CA, United States
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Organizing company knowledge
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HQ: San Francisco, CA, United States
What they do:
Infrastructure for building and scaling AI-native businesses.
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HQ: San Francisco, CA, United States
What they do:
AI-native test infrastructure layer for hardware companies
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HQ: San Francisco, CA, United States
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The social trading app for stocks, memes, and perps
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HQ: San Francisco, CA, United States
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Agentic procurement & inventory for deep tech teams.
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What they do:
Oura Ring for Skin
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HQ: San Francisco, CA, United States
What they do:
The identity and communication layer for AI agents
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HQ: San Francisco, CA, United States
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We find flaws in RL environments and evals and help you fix them.
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HQ: San Francisco, CA, United States
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Florin is an AI-native insurance company that runs autonomously
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HQ: San Francisco, CA, United States
What they do:
Internal industrial company data for frontier labs
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HQ: San Francisco, CA, United States
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Autoresearch as a service: we solve your hardest measurable problems
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HQ: San Francisco, CA, United States
What they do:
Evals for robots
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HQ: San Francisco, CA, United States
What they do:
Model Agnostic AI coworker in Slack
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HQ: San Francisco, CA, United States
What they do:
Discover novel defense related materials/molecules.
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HQ: Haifa, Israel
What they do:
Wet lab infrastructure that turns AI experiments into training data.
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HQ: San Francisco, CA, United States
What they do:
See and control what your agents actually do
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HQ: San Francisco, CA, United States
What they do:
Predictive maintenance for power infrastructure.
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HQ: Baltimore, MD, United States
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An AI-operated logistics company.
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HQ: San Francisco, CA, United States
What they do:
Embodied Scientific Intelligence
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HQ: San Francisco, CA, United States
What they do:
Maximum information per experiment, minimum experiments per conclusion
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HQ: Lund, Sweden
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An AI bracelet that remembers your day and acts before you ask.
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HQ: San Francisco, CA, United States
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Motor cortex for physical AI
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HQ: San Francisco, CA, United States
What they do:
Continuous optimization for AI agents
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HQ: San Francisco, CA, United States