Quick facts:
HQ: Boston, MA, United States
Incorporated: 2023
Funding:
$2.8M · Equity · Feb 2026
Top B2B Software Startups in Boston
This list has 65 startups and was last updated on Oct 15, 2026. 6 of them are hiring right now. Largest teams: Ginkgo Bioworks, TetraScience, and Cloudant. Latest round: Flexxbotics raised $1.8M (Oct 8, 2026).
65 startupsPage 2 of 2
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2023
Funding:
$2.06M · Equity · Feb 2026
Quick facts:
HQ: Boston, MA, United States
Funding:
$1.8M · Equity · Oct 2026
Quick facts:
HQ: Boston, MA, United States
Funding:
$1.5M · SAFE · Mar 2026
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2023
Funding:
$1.28M · Debt · Apr 2026
Quick facts:
HQ: Boston, MA, United States
Incorporated: 2025
Funding:
$100K · SAFE · Oct 2026
Cloudant
Acquired
What they do:
NoSQL Database-aaS. Acquired by IBM in 2014. Now IBM Cloud Data…
Quick facts:
HQ: Boston, MA, United States
Vendr
Acquired
What they do:
The AI negotiation agent to help you save money on SaaS.
Quick facts:
HQ: Boston, MA, United States
Sandbox Banking
Acquired
What they do:
Low-code integration platform for banking
Quick facts:
HQ: Boston, MA, United States
Moltin
Acquired
What they do:
eCommerce building blocks through simple APIs for websites & apps.…
Quick facts:
HQ: Boston, MA, United States
Ascen
Acquired
What they do:
EOR for the staffing industry
Quick facts:
HQ: Boston, MA, United States
Impactive (formerly Outvote)
Acquired
What they do:
Political/civic tech helping progressive campaigns organize & mobilize
Quick facts:
HQ: Boston, MA, United States
Gaiascope
Acquired
What they do:
SaaS that helps renewables & energy storage operate more profitably
Quick facts:
HQ: Boston, MA, United States
Pretty Instant
Acquired
What they do:
Inventor of the first roaming-photo booth + pro photography platform
Quick facts:
HQ: Boston, MA, United States
Bytebot
Acquired
What they do:
Bytebot is the open source container for AI desktop agents.
Quick facts:
HQ: Boston, MA, United States
Embedly
Acquired
What they do:
Embedly provides a platform and suite of tools to make embedding and previewing links simple. Embedly helps publishers and consumers manage embed codes from…
Quick facts:
HQ: Boston, MA, United States
Kiko
Acquired
What they do:
We're the best online calendar solution to ever exist. Period.
Quick facts:
HQ: Boston, MA, United States
YC S05Early stage
Hunter2
Acquired
What they do:
Hunter2 trains engineering teams in application security through…
Quick facts:
HQ: Boston, MA, United States
YC W18Early stage
Mindmesh
Shut down
What they do:
Mindmesh is the virtual desk that puts you in control.
Quick facts:
HQ: Boston, MA, United States
Ubiq
Shut down
What they do:
Screen-sharing for enterprise conference rooms
Quick facts:
HQ: Boston, MA, United States
Goodly
Shut down
What they do:
Student loan repayment as an employee benefit.
Quick facts:
HQ: Boston, MA, United States
WireOver
Shut down
What they do:
Really secure file sending for big files.
Quick facts:
HQ: Boston, MA, United States
Hipmob
Shut down
What they do:
Customer communication for iOS and Android developers - an in-app…
Quick facts:
HQ: Boston, MA, United States
DevFlight
Shut down
What they do:
Managed equipment data pipelines for manufacturers
Quick facts:
HQ: Boston, MA, United States
Bensen
Shut down
What they do:
Online and phone ordering for restaurant takeout and delivery
Quick facts:
HQ: Boston, MA, United States
CO2Stats
Shut down
What they do:
Social and environmental web analytics. Acquired in December 2016.
Quick facts:
HQ: Boston, MA, United States
YC S08Early stage
Audiobeta
Shut down
What they do:
AudioBeta develops web-based applications that helps bands communicate with fans and make informed decisions when planning tours. AudioBeta is a U.S.-based…
Quick facts:
HQ: Boston, MA, United States
YC W06Early stage
Memamp
Shut down
What they do:
Better Desktop search solution.
Quick facts:
HQ: Boston, MA, United States
YC S05Early stage
Eivod
Shut down
Quick facts:
HQ: Boston, MA, United States