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Top B2B Software Startups in Boston

This list has 65 startups and was last updated on Oct 15, 2026. 6 of them are hiring right now. Largest teams: Ginkgo Bioworks, TetraScience, and Cloudant. Latest round: Flexxbotics raised $1.8M (Oct 8, 2026).

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Questions and answers

How many startups are on this list?

There are 65 startups on this list, last updated on Oct 15, 2026.

Which of them are hiring?

6 of them are hiring right now, including Ginkgo Bioworks, Kodex, and Alpha Vantage.

Which of them have the largest teams?

By team size: Ginkgo Bioworks (641 employees), TetraScience (100 employees), and Cloudant (51 employees).

Which of them raised money recently?

Latest rounds: Flexxbotics — $1.8M Equity (Oct 2026), SkyNexus AI — $100K SAFE (Oct 2026), and Acumino — $11.7M Equity (Jun 2026).