What they do:
Helping healthcare providers reduce administrative costs using AI
Quick facts:
HQ: New York, NY, United States
Top B2B Software Startups in New York
This list has 555 startups and was last updated on Oct 15, 2026. 164 of them are hiring right now. Largest teams: Nabis, Guesty, and ACLU. Latest round: Weston AI raised $150K (Oct 13, 2026).
555 startupsPage 5 of 16
What they do:
Modernizing hedge fund back office software and services.
Quick facts:
HQ: New York, NY, United States
Arpari
Hiring
What they do:
Multibank treasury management
Quick facts:
HQ: New York, NY, United States
Cardinal Gray
Hiring
What they do:
Automating lenders' interactions with the DMV
Quick facts:
HQ: New York, NY, United States
Converge
Hiring
What they do:
All-in-one marketing measurement for B2C
Quick facts:
HQ: New York, NY, United States
Yarn
Hiring
What they do:
Yarn is the video product for agentic GTM teams.
Quick facts:
HQ: New York, NY, United States
Raycaster
Hiring
What they do:
Agentic AI for knowledge work
Quick facts:
HQ: New York, NY, United States
Trata
Hiring
What they do:
AI-powered research desk for hedge funds
Quick facts:
HQ: New York, NY, United States
Mbodi AI
Hiring
What they do:
Industrial Robots that Learn and Operate Like Humans
Quick facts:
HQ: New York, NY, United States
Voyager
Hiring
What they do:
Open harness for video and other creative work.
Quick facts:
HQ: New York, NY, United States
What they do:
Software to accelerate construction by finding issues in 3D BIM
Quick facts:
HQ: New York, NY, United States
Attack Capital
Hiring
What they do:
Access the start-up asset class with vetted private companies
Quick facts:
HQ: New York, NY, United States
Beam
Hiring
What they do:
AI-Native Cloud Platform
Quick facts:
HQ: New York, NY, United States
Capix
Hiring
What they do:
AI-powered private equity intelligence.
Quick facts:
HQ: New York, NY, United States
What they do:
Plaid for supply chain logistics
Quick facts:
HQ: New York, NY, United States
Kyber
Hiring
What they do:
Instantly draft, review, and send complex regulatory notices.
Quick facts:
HQ: New York, NY, United States
Type
Hiring
What they do:
AI-native storytelling studio.
Quick facts:
HQ: New York, NY, United States
Cedana
Hiring
What they do:
Fast, reliable, reproducible AI with GPU live migration
Quick facts:
HQ: New York, NY, United States
Sola
Hiring
What they do:
Copilot for Robotic Process Automation
Quick facts:
HQ: New York, NY, United States
Simbie AI
Hiring
What they do:
We get patients to their next appointment
Quick facts:
HQ: New York, NY, United States
ProhostAI
Hiring
What they do:
AI Property Manager for Airbnb & Short-Term Rental Hosts
Quick facts:
HQ: New York, NY, United States
Ryvn
Hiring
What they do:
Easy and secure customer cloud deployments
Quick facts:
HQ: New York, NY, United States
Liquid Compute
Hiring
What they do:
Pending CFTC regulation to be the first cash and physically settled…
Quick facts:
HQ: New York, NY, United States
Photonium
Hiring
What they do:
AI-Powered Optical Consulting & Software
Quick facts:
HQ: New York, NY, United States
Channel3
Hiring
What they do:
Database of every product on the internet
Quick facts:
HQ: New York, NY, United States
Wayco
Hiring
What they do:
AI operator for medlegal cases
Quick facts:
HQ: New York, NY, United States
Pango
Hiring
What they do:
Agentic OS for e-commerce operations
Quick facts:
HQ: New York, NY, United States
What they do:
The digital storefront for staffing and recruiting teams.
Quick facts:
HQ: New York, NY, United States
What they do:
The world's fastest calendar, beautifully designed for remote teams.
Quick facts:
HQ: New York, NY, United States
Dataland
Hiring
What they do:
AI agents for customer support.
Quick facts:
HQ: New York, NY, United States
What they do:
Visually design and manage cloud infrastructures.
Quick facts:
HQ: New York, NY, United States
Postal
Hiring
What they do:
An AI native virtual address & mailroom for businesses.
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HQ: New York, NY, United States
Vendora
Hiring
What they do:
All-in-One Software for the $1T Grocery Industry
Quick facts:
HQ: New York, NY, United States
Rulebase
Hiring
What they do:
AI customer operations for regulated industries.
Quick facts:
HQ: New York, NY, United States
Ambral
Hiring
What they do:
AI for account management and customer success
Quick facts:
HQ: New York, NY, United States
What they do:
The autonomous ERP for every manufacturer
Quick facts:
HQ: New York, NY, United States