What they do:
IP operating software for brands and content companies
Quick facts:
HQ: Los Angeles, CA, United States
Top B2B Software Startups in the United States
This list has 3,865 startups and was last updated on Oct 15, 2026. 827 of them are hiring right now. Biggest hubs: San Francisco (2,110), New York (555), and Los Angeles (79). Largest teams: Stripe, Deel, and GrubMarket. Latest round: Onebrief raised $151M (Oct 14, 2026).
3,865 startupsPage 3 of 108
What they do:
Modern employee benefits & health savings account (HSA) provider
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HQ: San Francisco, CA, United States
What they do:
Jasper is a leader in creating content using Artificial Intelligence
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HQ: Austin, TX, United States
Vouch
Hiring
What they do:
Insurance and risk management tools for startups and growth-stage…
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HQ: Chicago, IL, United States
What they do:
Simplifying hiring and payments for the global workforce
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HQ: Miami, FL, United States
Vetcove
Hiring
What they do:
Powering the animal health supply chain.
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HQ: Miami, FL, United States
What they do:
Robotic Process Automation and Document Processing Platform
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HQ: Austin, TX, United States
Pave
Hiring
What they do:
Plan, communicate, and benchmark your compensation in real-time.
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HQ: San Francisco, CA, United States
Remi
Hiring
What they do:
Simplifying roofing for homeowners, roofers and enterprises.
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HQ: Lehi, UT, United States
What they do:
Observability platform to control all of your log data
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HQ: San Francisco, CA, United States
What they do:
Building the Operating System for B&M Retail using Deep Learning
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HQ: San Francisco, CA, United States
Modern Treasury
Hiring
What they do:
Payment operations tools for money movement.
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HQ: San Francisco, CA, United States
RevenueCat
Hiring
What they do:
Build and grow your app business
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HQ: San Francisco, CA, United States
OneSignal
Hiring
What they do:
Engage customers through personalized omni-channel messaging
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HQ: San Francisco, CA, United States
Lob
Hiring
What they do:
Lob is the only automation platform that transforms direct mail into…
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HQ: New York, NY, United States
Mashgin
Hiring
What they do:
Self-Checkout using Computer Vision.
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HQ: San Francisco, CA, United States
Ambient.ai
Hiring
What they do:
AI company transforming enterprise physical security to prevent…
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HQ: San Francisco, CA, United States
Standard AI
Hiring
What they do:
AI-powered checkout for retail.
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HQ: San Francisco, CA, United States
Canary Technologies
Hiring
What they do:
Modernizing the hospitality tech stack.
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HQ: New York, NY, United States
Alpaca
Hiring
What they do:
API-first stock and crypto brokerage platform
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HQ: San Francisco, CA, United States
InEvent
Hiring
What they do:
In-Person, Hybrid and Virtual Event Management Software
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HQ: Atlanta, GA, United States
PostHog
Hiring
What they do:
The single platform to analyze, test, observe, and deploy new features
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HQ: San Francisco, CA, United States
Gigs
Hiring
What they do:
The OS for Embedded Telecom
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HQ: San Francisco, CA, United States
What they do:
The cloud-native, operational database built for speed and scale.
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HQ: San Francisco, CA, United States
Bitmovin
Hiring
What they do:
Powers OTT online video providers with video developer tools.
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HQ: San Francisco, CA, United States
What they do:
Get matched with top 1% of talents in 24h
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HQ: San Francisco, CA, United States
Middesk
Hiring
What they do:
We make it easier for B2B companies to transact with one another
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HQ: San Francisco, CA, United States
What they do:
Zerocater is revolutionizing how companies feed their employees
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HQ: Chicago, IL, United States
What they do:
Deliver on the Promise of Design
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HQ: San Francisco, CA, United States
What they do:
We help US tech companies hire and manage software engineers in LATAM
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HQ: Austin, TX, United States
GiveCampus
Hiring
What they do:
The fundraising platform for schools.
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HQ: Washington, DC, United States
Numeral
Hiring
What they do:
The AI-native sales tax solution.
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HQ: San Francisco, CA, United States
Within
Hiring
What they do:
Company Brain for people and agents to work in harmony.
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HQ: San Francisco, CA, United States
What they do:
Protocol Labs makes internet protocols: IPFS, Filecoin, and more.
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HQ: San Francisco, CA, United States
What they do:
On-demand prescription delivery.
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HQ: San Francisco, CA, United States
Abacum
Hiring
What they do:
The AI-native FP&A platform that helps Finance teams drive business…
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HQ: New York, NY, United States