What they do:
Enzyme design models.
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HQ: San Francisco, CA, United States
Top Climate & Energy Startups in the United States
This list has 236 startups and was last updated on Oct 15, 2026. 26 of them are hiring right now. Biggest hubs: San Francisco (90), New York (15), and Los Angeles (12). Largest teams: Cruise, Zeitview, and Solugen. Latest round: Circularity Fuels raised $8.79M (Oct 14, 2026).
236 startupsPage 3 of 7
What they do:
Building a nervous system for the atmosphere
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HQ: San Francisco, CA, United States
What they do:
We build floating solar data centers
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HQ: San Francisco, CA, United States
What they do:
Streamlining Data Capture to Report Creation for Heavy Industries
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HQ: San Francisco, CA, United States
What they do:
Robots that run autonomous depots for autonomous fleets.
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HQ: San Francisco, CA, United States
What they do:
We turn waste gases into supply-secure chemicals
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HQ: Chicago, IL, United States
What they do:
Microgrids in a box built anywhere in days
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HQ: San Francisco, CA, United States
What they do:
Skyscrape makes temperature-responsive insulation
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HQ: Portland, OR, United States
What they do:
Cutting edge hydrofoil systems for boatbuilders
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HQ: San Francisco, CA, United States
What they do:
High precision AI weather
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HQ: Ann Arbor, MI, United States
What they do:
Batteries and solar for $0 upfront to help businesses save money
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HQ: San Francisco, CA, United States
What they do:
A stealth mode startup.
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HQ: San Francisco, CA, United States
What they do:
Engineering microbes for miners to unlock billions in trapped metal
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HQ: San Francisco, CA, United States
What they do:
Predictive maintenance for power infrastructure.
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HQ: Baltimore, MD, United States
What they do:
Growing seaweed to stabilize the climate.
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HQ: San Francisco, CA, United States
What they do:
Building a frontier world model for power
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HQ: Los Angeles, CA, United States
What they do:
Genetically engineering plants for disease resistance.
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HQ: San Francisco, CA, United States
What they do:
Platform for cities to optimize transit
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HQ: New York, NY, United States
What they do:
AI-native remote operations center for hardware fleets
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HQ: San Francisco, CA, United States
What they do:
Powering tomorrow's industrial revolution in space
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HQ: San Diego, CA, United States
What they do:
The robot workforce for infrastructure
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HQ: San Francisco, CA, United States
What they do:
Drones that clear clouds over solar farms and weaken hurricanes
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HQ: San Francisco, CA, United States
What they do:
Hyper-efficient coolers for data centers
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HQ: San Francisco, CA, United States
What they do:
Simulating Agents Running Industrial Companies
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HQ: San Francisco, CA, United States
What they do:
AI-Native Engineering Firm designing Data Centers
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HQ: San Francisco, CA, United States
What they do:
We make silicon on the Moon, to power everything in space.
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HQ: Los Angeles, CA, United States
What they do:
Deploying robots to replace workers in hazardous spaces
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HQ: San Francisco, CA, United States
What they do:
Floating nuclear powered data centers at sea.
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HQ: San Francisco, CA, United States
What they do:
AI for the industries that power America.
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HQ: San Francisco, CA, United States
What they do:
The operating system for commercial buildings.
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HQ: Niagara Falls, NY, United States
What they do:
Prime Lightworks Inc. manufactures electric propulsion systems for…
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HQ: Culver City, CA, United States
What they do:
Power-ready land for AI data centers
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HQ: New York, NY, United States
What they do:
Eclipse Foods is building the future of dairy using micelles, the…
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HQ: San Francisco, CA, United States
YC W19Growth stage
What they do:
We make the most compact nuclear reactors
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HQ: Boston, MA, United States
YC X26Early stage
What they do:
We help Fortune 500 companies hedge their supply chain risk
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HQ: San Francisco, CA, United States
YC S26Early stage
Cruise
Acquired
What they do:
Self-driving cars.
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HQ: San Francisco, CA, United States