What they do:
Patient engagement for low-income populations
Quick facts:
HQ: Austin, TX, United States
Top Digital Health Startups in Texas
This list has 13 startups and was last updated on Oct 15, 2026. 3 of them are hiring right now. Biggest hubs: Austin (7) and Houston (2). Largest teams: Evry Health, CareMessage, and Ankr Health. Latest round: USA Emergency Centers - San Marcos raised $2.4M (Jun 3, 2026).
13 startups
Ankr Health
Hiring
What they do:
Virtualizing brick-mortar infrastructures of clinics w/ generative AI
Quick facts:
HQ: Houston, TX, United States
HealthKey
Hiring
What they do:
AI-powered Patient Identification for Clinical Trials
Quick facts:
HQ: Austin, TX, United States
Akute Health
Hiring
What they do:
The medical record & infrastructure stack for digital health companies
Quick facts:
HQ: Austin, TX, United States
What they do:
AI enabling digital urine diagnostics in the home
Quick facts:
HQ: Houston, TX, United States
What they do:
Stripe for medical billing
Quick facts:
HQ: Austin, TX, United States
What they do:
AI agents on real phones, growing brands across every platform.
Quick facts:
HQ: Austin, TX, United States
Quick facts:
HQ: Frisco, TX, United States
Funding:
$7M · Equity · May 2026
Quick facts:
HQ: Texas City, TX, United States
Incorporated: 2025
Funding:
$2.6M · Equity + debt · May 2026
Quick facts:
HQ: Austin, TX, United States
Incorporated: 2025
Funding:
$2.4M · Equity · Jun 2026
Quick facts:
HQ: Pantego, TX, United States
Incorporated: 2026
Funding:
$1.6M · Equity · May 2026
Evry Health
Acquired
What they do:
Better health insurance for mid-size companies
Quick facts:
HQ: Dallas, TX, United States
Covie
Shut down
What they do:
Programmatic building blocks for transacting with insurance
Quick facts:
HQ: Austin, TX, United States
Questions and answers
How many startups are on this list?
There are 13 startups on this list, last updated on Oct 15, 2026.
Which of them are hiring?
3 of them are hiring right now, including Ankr Health, HealthKey, and Akute Health.
Which of them have the largest teams?
By team size: Evry Health (87 employees), CareMessage (45 employees), and Ankr Health (30 employees).
Which of them raised money recently?
Latest rounds: USA Emergency Centers - San Marcos — $2.4M Equity (Jun 2026), International Hospital Corp/Tx — $7M Equity (May 2026), and Saint Raphael Health — $2.6M Equity + debt (May 2026).
Where are they based?
The biggest hubs are Austin (7) and Houston (2).